Unsupervised learning - i.e., learning with unlabeled data - is increasingly important given today\u27s data deluge. Most natural problems in this domain - e.g. for models such as mixture models, HMMs, graphical models, topic models and sparse coding/dictionary learning, deep learning - are NP-hard. Therefore researchers in practice use either heuristics or convex relaxations with no concrete approximation bounds. Several nonconvex heuristics work well in practice, which is also a mystery. The talk will describe a sequence of recent results whereby rigorous approaches leading to polynomial running time are possible for several problems in unsupervised learning. The proof of polynomial running time usually relies upon nondegeneracy assumpti...