A DETAILED STUDY OF RELEVANT FACTORS FOR MACROANGIOPATHY IN DIABETES MELLITUS

The major risk factors of diabetic macroangiopathy and the associations between macroangiopathy and microangiopathy were examined in a cross-sectional study by multi-factorial analysis. The study group comprised 544 diabetics admitted between 1982 and 1991, of whom 350 were fully available for analysis. Variables used in this analysis included current age, age at onset, diabetes duration, obesity, hypertension, hyperlipidemia, ischemic heart disease (IHD), cerebro-vascular disease (CVD), arteriosclerosis obliterans (ASO), nephropathy, retinopathy and treatment modality. Results were as follows : (1) IHD was closely associated with onset at 50s and 60s, disease duration of 5 to 9 years, and oral agent ; (2) CVD was closely associated with aging, disease duration of 10 to 14 years, simple retinopathy, and oral agent ; (3) ASO was closely associated with disease duration of more than 15 years and persistent proteinuria