Add to ORKGHyperthermia is widely used to treat patients with various types of cancers. However, the molecular mechanisms involved in heat-induced cell killing are not yet fully understood. Although protein denaturation is known to be a major type of damage caused by heat treatment, recent work has revealed that DNA double-strand breaks (DSBs) play important roles in heat-induced cell killing. The aim of this review is to specifically examine the formation and repair of DSBs and their role in heat sensitivity and thermotolerance.著作権者：日本ハイパーサーミア学会日本ハイパーサーミア学会及び著作者の許諾を得て登
Ionizing radiation induces a range of different DNA lesions. In terms of mutation frequency and mamm...
Ionizing radiation induces a range of different DNA lesions. In terms of mutation frequency and mamm...
Ionizing radiation induces a range of different DNA lesions. In terms of mutation frequency and mamm...
Currently, the molecular mechanisms involved in heat-induced cell killing are not completely underst...
DNA double-strand breaks (DSBs) are the most deleterious lesions that can arise in cells after ioniz...
DNA double-strand breaks (DSBs) are the most deleterious lesions that can arise in cells after ioniz...
DNA double-strand breaks (DSBs) are the most deleterious lesions that can arise in cells after ioniz...
DNA double-strand breaks (DSBs) are the most deleterious lesions that can arise in cells after ioniz...
The currently available arsenal of anticancer modalities includes many DNA damaging agents that can ...
<div><p><i>Purpose</i>: Radiation with high linear energy transfer (LET) produces clustering of DNA ...
Hyperthermia inhibits DNA double-strand break (DSB) repair that utilizes homologous recombination (H...
Hyperthermia is used as an adjuvant in the chemo- and radiotherapy of cancer. Besides a direct celki...
Direct heat exposure to cells causes protein degradation and DNA damage, which can lead to genetic a...
The effect of heat on double-strand breaks (dsb) repair was compared with thermal radiosensitization...
The effect of heat on double-strand breaks (dsb) repair was compared with thermal radiosensitization...
Ionizing radiation induces a range of different DNA lesions. In terms of mutation frequency and mamm...
Ionizing radiation induces a range of different DNA lesions. In terms of mutation frequency and mamm...
Ionizing radiation induces a range of different DNA lesions. In terms of mutation frequency and mamm...
Currently, the molecular mechanisms involved in heat-induced cell killing are not completely underst...
DNA double-strand breaks (DSBs) are the most deleterious lesions that can arise in cells after ioniz...
DNA double-strand breaks (DSBs) are the most deleterious lesions that can arise in cells after ioniz...
DNA double-strand breaks (DSBs) are the most deleterious lesions that can arise in cells after ioniz...
DNA double-strand breaks (DSBs) are the most deleterious lesions that can arise in cells after ioniz...
The currently available arsenal of anticancer modalities includes many DNA damaging agents that can ...
<div><p><i>Purpose</i>: Radiation with high linear energy transfer (LET) produces clustering of DNA ...
Hyperthermia inhibits DNA double-strand break (DSB) repair that utilizes homologous recombination (H...
Hyperthermia is used as an adjuvant in the chemo- and radiotherapy of cancer. Besides a direct celki...
Direct heat exposure to cells causes protein degradation and DNA damage, which can lead to genetic a...
The effect of heat on double-strand breaks (dsb) repair was compared with thermal radiosensitization...
The effect of heat on double-strand breaks (dsb) repair was compared with thermal radiosensitization...
Ionizing radiation induces a range of different DNA lesions. In terms of mutation frequency and mamm...
Ionizing radiation induces a range of different DNA lesions. In terms of mutation frequency and mamm...
Ionizing radiation induces a range of different DNA lesions. In terms of mutation frequency and mamm...