No studies have addressed the question of whether metformin reduces development of diabetes among adolescents who are obese. Metformin treatment in adolescents who are obese can modestly reduce risk factors for type 2 diabetes, including elevated body mass index (BMI), fasting insulin levels, and fasting glucose levels. (Strength of Recommendation [SOR]: C). However, metformin treatment is associated with nausea, abdominal pain, and diarrhea. (SOR: A). Because of the limited available data, metformin is not recommended for diabetes prevention in adolescents. (SOR: C)
BACKGROUND: Metformin treatment (1000-2000 mg/day) over 6 months in pubertal children and/or adolesc...
Manuscript abstract: CONTEXT: Insulin resistance has been proposed as one of the causes of poor glyc...
BACKGROUND: As adolescents with obesity and insulin resistance may be refractory to lifestyle interv...
There are no studies evaluating whether metformin prevents or delays the onset of diabetes in adoles...
Introduction: In the United States, overweight adolescents are likely to continue to gain weight ove...
OBJECTIVE — To summarize the efficacy of metformin in reducing BMI and cardiometa-bolic risk in obes...
OBJECTIVE—Metformin can decrease adiposity and ameliorate obesity-related comorbid conditions, inclu...
BACKGROUND: The prevalence of childhood obesity and insulin resistance is rising, increasing the ris...
Context: Childhood obesity is increasingly associated with type 2 diabetes (T2D). Metformin reduces ...
BACKGROUND: The prevalence of childhood obesity and insulin resistance is rising, increasing the ris...
One of the most challenging health conditions primary care providers face is combating the ever-risi...
Abstract: Background: Metformin therapy for adults and children with type 2 diabetes mellitus is wel...
Background. The effect of metformin in combination with insulin in adolescents with type 1 diabetes ...
Background: Pharmacological treatment of obesity and glucose-insulin metabolism disorders in childre...
BACKGROUND: As adolescents with obesity and insulin resistance may be refractory to lifestyle interv...
BACKGROUND: Metformin treatment (1000-2000 mg/day) over 6 months in pubertal children and/or adolesc...
Manuscript abstract: CONTEXT: Insulin resistance has been proposed as one of the causes of poor glyc...
BACKGROUND: As adolescents with obesity and insulin resistance may be refractory to lifestyle interv...
There are no studies evaluating whether metformin prevents or delays the onset of diabetes in adoles...
Introduction: In the United States, overweight adolescents are likely to continue to gain weight ove...
OBJECTIVE — To summarize the efficacy of metformin in reducing BMI and cardiometa-bolic risk in obes...
OBJECTIVE—Metformin can decrease adiposity and ameliorate obesity-related comorbid conditions, inclu...
BACKGROUND: The prevalence of childhood obesity and insulin resistance is rising, increasing the ris...
Context: Childhood obesity is increasingly associated with type 2 diabetes (T2D). Metformin reduces ...
BACKGROUND: The prevalence of childhood obesity and insulin resistance is rising, increasing the ris...
One of the most challenging health conditions primary care providers face is combating the ever-risi...
Abstract: Background: Metformin therapy for adults and children with type 2 diabetes mellitus is wel...
Background. The effect of metformin in combination with insulin in adolescents with type 1 diabetes ...
Background: Pharmacological treatment of obesity and glucose-insulin metabolism disorders in childre...
BACKGROUND: As adolescents with obesity and insulin resistance may be refractory to lifestyle interv...
BACKGROUND: Metformin treatment (1000-2000 mg/day) over 6 months in pubertal children and/or adolesc...
Manuscript abstract: CONTEXT: Insulin resistance has been proposed as one of the causes of poor glyc...
BACKGROUND: As adolescents with obesity and insulin resistance may be refractory to lifestyle interv...