Glucosamine and Chondroitin for Osteoarthritis

Glucosamine reduces pain and improves function in patients with knee or hip osteoarthritis. (Strength of recommendation: B, based on systematic reviews and a meta-analysis) Glucosamine may be beneficial in other forms of osteoarthritis as well. (Strength of recommendation: B, based on a randomized controlled trial [RCT]) Chondroitin has not consistently been found to improve pain or functional status. (Strength of recommendation: B, based on a systematic review and a meta-analysis