Refractory Eating Disorders in Youth: An Examination of Predictors, Profiles and Growth Trajectories

Eating disorders are known for their chronic and relapse-ridden course. The cyclical nature of these disorders poses not only grave physical and mental health risks for the sufferer; it also presents serious challenges for the treating professionals and places a high demand and cost on the health care system. In spite of extensive research, no reliable predictors of long-term EDs have been identified in either adult or adolescent populations, nor have treatments emerged that are specifically targeted towards treating those with a long-term ED. It is fundamental to understand who is at risk and what factors are involved in long-term EDs, as the clinical and treatment implications gleaned from this evidence could be quite impactful. The current project will include three studies that will explore long-term EDs in a large transdiagnostic sample of adolescents with an ED. It will also attempt to overcome methodological limitations associated with past studies of this type, and apply an operational definition of this course of illness that may provide a more reliable and valid method with which to identify these cases. As such, the use of the term refractory ED, defined as a return to same-type treatment, will be applied to best identify this group. The three studies proposed in this research project will provide long overdue information on predictors, profiles and growth trajectories of those adolescents who suffer from a refractory course of an ED. This research project attempts to answer the question of: who will be affected, and how will the individual be affected by a refractory ED. With the ability to identify these cases and how the course of illness is being affected, treatment approaches can better aim to provide the appropriate treatment to those individuals most at risk of suffering from a refractory course of illness