Add to ORKGOncolytic viruses are currently under investigation as anti - cancer therapies due to their innate ability to selectively infect and destroy cancer cells. Major barriers to this anti - tumour effect include inefficient viral spread and immune - mediated neutralization. This study aims to overcome these limitations by taking advantage of the life cycle of the oncolytic clinical candidate known as vaccinia virus (VACV). Naturally, a small proportion (<1%) of VACV progeny are released from infected cells with a cell - derived membrane and become known as extra - cellular enveloped virus (EEV). Due to this additional membrane, EEV can be shielded from many anti -viral immune factors , allowing it to travel further and largely avoid host...
Many oncolytic viruses (OVs), such as double-deleted vaccina virus (vvDD), are engineered with enhan...
Many oncolytic viruses (OVs), such as double-deleted vaccina virus (vvDD), are engineered with enhan...
Several wild-type poxviruses have emerged as potential oncolytic viruses (OVs), including orf virus ...
The use of oncolytic viruses for the treatment of cancer is an emerging field of cancer research and...
Oncolytic virus (OV) therapy has emerged as a promising approach for cancer treatment with the poten...
Oncolytic virus (OV) therapy has emerged as a promising approach for cancer treatment with the poten...
Vaccinia Virus (VACV) is well-known as the vaccine used for the eradication of smallpox. It serves a...
Vaccinia virus has a large and still incompletely understood genome although several strains of this...
Abstract Background We have shown that insertion of the three vaccinia virus (VACV) promoter-driven ...
Vaccinia virus (VV) has emerged as a promising platform for oncolytic virotherapy. Many clinical VV ...
Background: We have shown that insertion of the three vaccinia virus (VACV) promoter-driven fore...
Oncolytic abilities of vaccinia virus (VACV) served as a basis for the development of various recomb...
Oncolytic virotherapy has emerged as a novel form of cancer immunotherapy. Oncolytic viruses (OVs) c...
Oncolytic vaccinia viruses have promising efficacy and safety profiles in cancer therapy. Although a...
Increasing incidence of antimicrobial resistance requires identification of novel drugs, and the hum...
Many oncolytic viruses (OVs), such as double-deleted vaccina virus (vvDD), are engineered with enhan...
Many oncolytic viruses (OVs), such as double-deleted vaccina virus (vvDD), are engineered with enhan...
Several wild-type poxviruses have emerged as potential oncolytic viruses (OVs), including orf virus ...
The use of oncolytic viruses for the treatment of cancer is an emerging field of cancer research and...
Oncolytic virus (OV) therapy has emerged as a promising approach for cancer treatment with the poten...
Oncolytic virus (OV) therapy has emerged as a promising approach for cancer treatment with the poten...
Vaccinia Virus (VACV) is well-known as the vaccine used for the eradication of smallpox. It serves a...
Vaccinia virus has a large and still incompletely understood genome although several strains of this...
Abstract Background We have shown that insertion of the three vaccinia virus (VACV) promoter-driven ...
Vaccinia virus (VV) has emerged as a promising platform for oncolytic virotherapy. Many clinical VV ...
Background: We have shown that insertion of the three vaccinia virus (VACV) promoter-driven fore...
Oncolytic abilities of vaccinia virus (VACV) served as a basis for the development of various recomb...
Oncolytic virotherapy has emerged as a novel form of cancer immunotherapy. Oncolytic viruses (OVs) c...
Oncolytic vaccinia viruses have promising efficacy and safety profiles in cancer therapy. Although a...
Increasing incidence of antimicrobial resistance requires identification of novel drugs, and the hum...
Many oncolytic viruses (OVs), such as double-deleted vaccina virus (vvDD), are engineered with enhan...
Many oncolytic viruses (OVs), such as double-deleted vaccina virus (vvDD), are engineered with enhan...
Several wild-type poxviruses have emerged as potential oncolytic viruses (OVs), including orf virus ...