During neuronal development, the axonal and dendritic projections are polarized and oriented along specific body axis. To further explore the molecular basis of neuritogenesis in vivo, we used the nematode Caenorhabditis elegans as a developmental model and performed a forward genetic screen to identify genes that specify the polarity of neurite outgrowth. We examined the VC4 and VC5 neurons, members of the six VC motor neurons using the Pcat-
BackgroundNeurons assemble into a functional network through a sequence of developmental processes i...
AbstractUnderstanding how epithelial organs form during morphogenesis is a major problem in developm...
The development of a polarized neuron relies on the selective transport of proteins to axons and den...
The correct polarity of a neuron underlies its ability to integrate precise circuitries in the nervo...
Little is known about the molecular components and interactions of the planar cell polarity pathway ...
Van Gogh-like (Vangl) and Prickle (Pk) are core components of the non-canonical Wnt planar cell pola...
Van Gogh-like (Vangl) and Prickle (Pk) are core components of the non-canonical Wnt planar cell pola...
Cellular polarization is an important aspect of neural development. During the development of the C....
Cellular polarization is critical for many stages of neuronal development, including the asymmetric ...
The transmembrane protein Vangl2, a key regulator of the Wnt/planar cell polarity (PCP) pathway, is ...
The term polarity in a biological context is used to describe an asymmetry in morphology and distrib...
Signaling that instructs the migration of neurons needs to be tightly regulated to ensure precise po...
AbstractDuring embryonic development neurons differentiate and extend axons and dendrites that have ...
The Wnt family of secreted proteins is responsible for a multitude of developmental processes, ofte...
AbstractDirected axonal growth is essential to establish neuronal networks. During the early develop...
BackgroundNeurons assemble into a functional network through a sequence of developmental processes i...
AbstractUnderstanding how epithelial organs form during morphogenesis is a major problem in developm...
The development of a polarized neuron relies on the selective transport of proteins to axons and den...
The correct polarity of a neuron underlies its ability to integrate precise circuitries in the nervo...
Little is known about the molecular components and interactions of the planar cell polarity pathway ...
Van Gogh-like (Vangl) and Prickle (Pk) are core components of the non-canonical Wnt planar cell pola...
Van Gogh-like (Vangl) and Prickle (Pk) are core components of the non-canonical Wnt planar cell pola...
Cellular polarization is an important aspect of neural development. During the development of the C....
Cellular polarization is critical for many stages of neuronal development, including the asymmetric ...
The transmembrane protein Vangl2, a key regulator of the Wnt/planar cell polarity (PCP) pathway, is ...
The term polarity in a biological context is used to describe an asymmetry in morphology and distrib...
Signaling that instructs the migration of neurons needs to be tightly regulated to ensure precise po...
AbstractDuring embryonic development neurons differentiate and extend axons and dendrites that have ...
The Wnt family of secreted proteins is responsible for a multitude of developmental processes, ofte...
AbstractDirected axonal growth is essential to establish neuronal networks. During the early develop...
BackgroundNeurons assemble into a functional network through a sequence of developmental processes i...
AbstractUnderstanding how epithelial organs form during morphogenesis is a major problem in developm...
The development of a polarized neuron relies on the selective transport of proteins to axons and den...