Neuropeptide Y (NPY) is a 36 amino acid peptide that is co-stored and co-released with noradrenaline from perivascular sympathetic nerves. In the present project, I tested the hypothesis that the vasopressor effect of NPY is related to its modulation of ion channel activities. The effects of NPY on Ca$\sp{2+}$-channel currents in freshly isolated vascular smooth muscle cells (VSMC) from the rat tail artery were studied with the perforated-patch recording technique. At a testing potential of +10 mV, the amplitude of inward current was increased by 46% in the presence of NPY 150 nM. The effects of NPY on both Ca$\sp{2+}$ current amplitude and steady-state activation were much weaker compared to the dihydropyridine agonist Bay K 8644. Unlike B...
Neuropeptide Y (NPY) is present in the brain, the adrenal medulla, and peripheral sympathetic nerves...
Neuropeptide Y (NPY) coexists and is coreleased with norepinephrine (NE) from postganglionic sympath...
The co-transmitter neuropeptide Y (NPY), released during prolonged cardiac sympathetic nerve stimula...
In the present study, the roles of nifedipine-sensitive calcium channels and the endothelium in the ...
1. In the present study we compared neuropeptide Y (NPY) and NPY-related analogues for their ability...
Abstract The aims of the present thesis were to examine neuropeptide Y (NPY) responses in different ...
AbstractThe effect of neuropeptide Y (NPY) on cytosolic free Ca2+ concentration ([Ca2+],) was studie...
AbstractObjectives. This study examined the coronary vasoconstrictive action of endogenous neuropept...
Neuropeptide Y (NPY-(1-36)) acts on Y1 and Y2 receptors at the sympathetic neuroeffector junction. V...
The aim of our study was to determine the neuropeptide Y (NPY) receptor subtype responsible for the ...
Neuropeptide Y (NPY), a sympathetic cotransmitter, acts via G protein-coupled receptors to stimulate...
Neuropeptide Y (NPY) increases blood pressure either directly or indirectly by potentiating the effe...
ATP, norepinephrine and NPY are co-released by sympathetic nerves innervating arteries. ATP elicits ...
Contraction of the guinea pig saphenous artery induced by stimulation of perivascular nerves consist...
In the heart, neuropeptide Y (NPY) released during stimulation of the sympathetic nerve attenuates v...
Neuropeptide Y (NPY) is present in the brain, the adrenal medulla, and peripheral sympathetic nerves...
Neuropeptide Y (NPY) coexists and is coreleased with norepinephrine (NE) from postganglionic sympath...
The co-transmitter neuropeptide Y (NPY), released during prolonged cardiac sympathetic nerve stimula...
In the present study, the roles of nifedipine-sensitive calcium channels and the endothelium in the ...
1. In the present study we compared neuropeptide Y (NPY) and NPY-related analogues for their ability...
Abstract The aims of the present thesis were to examine neuropeptide Y (NPY) responses in different ...
AbstractThe effect of neuropeptide Y (NPY) on cytosolic free Ca2+ concentration ([Ca2+],) was studie...
AbstractObjectives. This study examined the coronary vasoconstrictive action of endogenous neuropept...
Neuropeptide Y (NPY-(1-36)) acts on Y1 and Y2 receptors at the sympathetic neuroeffector junction. V...
The aim of our study was to determine the neuropeptide Y (NPY) receptor subtype responsible for the ...
Neuropeptide Y (NPY), a sympathetic cotransmitter, acts via G protein-coupled receptors to stimulate...
Neuropeptide Y (NPY) increases blood pressure either directly or indirectly by potentiating the effe...
ATP, norepinephrine and NPY are co-released by sympathetic nerves innervating arteries. ATP elicits ...
Contraction of the guinea pig saphenous artery induced by stimulation of perivascular nerves consist...
In the heart, neuropeptide Y (NPY) released during stimulation of the sympathetic nerve attenuates v...
Neuropeptide Y (NPY) is present in the brain, the adrenal medulla, and peripheral sympathetic nerves...
Neuropeptide Y (NPY) coexists and is coreleased with norepinephrine (NE) from postganglionic sympath...
The co-transmitter neuropeptide Y (NPY), released during prolonged cardiac sympathetic nerve stimula...