This paper considers the behavior of discrete and continuous mathematical models for gene expression in the presence of transcriptional/translational bursting. We treat this problem in generality with respect to the distribution of the burst size as well as the frequency of bursting, and our results are applicable to both inducible and repressible expression patterns in prokaryotes and eukaryotes. We have given numerous examples of the applicability of our results, especially in the experimentally observed situation that burst size is geometrically or exponentially distributed
Fitting the probability mass functions from analytical solutions of stochastic models of gene expres...
The bulk of stochastic gene expression models in the literature do not have an explicit description ...
arXiv. Mathematics. ProbabilityNon publiéThis paper considers adiabatic reduction in both discrete a...
22 pagesThis paper considers the behavior of discrete and continuous mathematical models for gene ex...
We present a theoretical framework to analyze the dynamics of gene expression with stochastic bursts...
AbstractTranscription is regulated by a multitude of factors that concertedly induce genes to switch...
Many inducible genes are transcribed in bursts. In this issue, Degenhardt et al. (2009) report compu...
Gene expression in individual cells is highly variable and sporadic, often resulting in the syn-thes...
We analyze transcriptional bursting within a stochastic nonequilibrium model, which accounts for the...
Gene transcription is a highly stochastic and dynamic process. As a result, the mRNA copy number of ...
<p>Recent analyses with high-resolution single-molecule experimental methods have shown highly irreg...
AbstractIn prokaryotes and eukaryotes, genes are transcribed stochastically according to various tem...
This paper considers adiabatic reduction in both discrete and continuous models of stochastic gene e...
Transcription occurs in stochastic bursts. Early models based upon RNA hybridisation studies suggest...
AbstractThe recent measurements of gene transcription activity at single cell resolution revealed th...
Fitting the probability mass functions from analytical solutions of stochastic models of gene expres...
The bulk of stochastic gene expression models in the literature do not have an explicit description ...
arXiv. Mathematics. ProbabilityNon publiéThis paper considers adiabatic reduction in both discrete a...
22 pagesThis paper considers the behavior of discrete and continuous mathematical models for gene ex...
We present a theoretical framework to analyze the dynamics of gene expression with stochastic bursts...
AbstractTranscription is regulated by a multitude of factors that concertedly induce genes to switch...
Many inducible genes are transcribed in bursts. In this issue, Degenhardt et al. (2009) report compu...
Gene expression in individual cells is highly variable and sporadic, often resulting in the syn-thes...
We analyze transcriptional bursting within a stochastic nonequilibrium model, which accounts for the...
Gene transcription is a highly stochastic and dynamic process. As a result, the mRNA copy number of ...
<p>Recent analyses with high-resolution single-molecule experimental methods have shown highly irreg...
AbstractIn prokaryotes and eukaryotes, genes are transcribed stochastically according to various tem...
This paper considers adiabatic reduction in both discrete and continuous models of stochastic gene e...
Transcription occurs in stochastic bursts. Early models based upon RNA hybridisation studies suggest...
AbstractThe recent measurements of gene transcription activity at single cell resolution revealed th...
Fitting the probability mass functions from analytical solutions of stochastic models of gene expres...
The bulk of stochastic gene expression models in the literature do not have an explicit description ...
arXiv. Mathematics. ProbabilityNon publiéThis paper considers adiabatic reduction in both discrete a...