Expression of genes of the locus of enterocyte effacement (LEE) is essential for adherence of enterohemorrhagic Escherichia coli (EHEC) to intestinal epithelial cells. Gut factors that may modulate LEE gene expression may therefore influence the outcome of the infection. Because nitric oxide (NO) is a critical effector of the intestinal immune response that may induce transcriptional regulation in enterobacteria, we investigated its influence on LEE expression in EHEC O157:H7. We demonstrate that NO inhibits the expression of genes belonging to LEE1, LEE4, and LEE5 operons, and that the NO sensor nitrite-sensitive repressor (NsrR) is a positive regulator of these operons by interacting directly with the RNA polymerase complex. In the presen...
UNLABELLED: Global regulator of virulence A (GrvA) is a ToxR-family transcriptional regulator that a...
Enterohemorrhagic Escherichia coli (EHEC) is dependent on acid resistance for gastric passage and lo...
UNLABELLED: Global regulator of virulence A (GrvA) is a ToxR-family transcriptional regulator that a...
Expression of genes of the locus of enterocyte effacement (LEE) is essential for adherence of entero...
<div><p>Expression of genes of the locus of enterocyte effacement (LEE) is essential for adherence o...
Enterohemorrhagic Escherichia coli (EHEC) is a foodborne pathogen causing hemorrhagic colitis and He...
Les Escherichia coli entérohémorragiques (EHEC) sont responsables de toxi-infections alimentaires co...
Enterohaemorrhagic Escherichia coli (EHEC) are bacterial pathogens responsible for life-threatening ...
Enterohaemorrhagic Escherichia coli (EHEC) are bacterial pathogens responsible for life-threatening ...
International audienceShiga-toxin (Stx) is the cardinal virulence factor of enterohemorrhagic Escher...
The locus of enterocyte effacement (LEE) encoded operons (LEE1 - LEE5) enable enterohemorrhagic Esch...
Enterohemorrhagic Escherichia coli (EHEC) is dependent on acid resistance for gastric passage and lo...
Background: Enteropathogenic E. coli (EPEC) and enterohemorrhagic E. coli are important causes of mo...
Enteropathogenic E. coli (EPEC) and enterohemorrhagic E. coli are important causes of morbidity and ...
Enterohaemorrhagic Escherichia coli (EHEC) pathogens represent major difficulties to health as they ...
UNLABELLED: Global regulator of virulence A (GrvA) is a ToxR-family transcriptional regulator that a...
Enterohemorrhagic Escherichia coli (EHEC) is dependent on acid resistance for gastric passage and lo...
UNLABELLED: Global regulator of virulence A (GrvA) is a ToxR-family transcriptional regulator that a...
Expression of genes of the locus of enterocyte effacement (LEE) is essential for adherence of entero...
<div><p>Expression of genes of the locus of enterocyte effacement (LEE) is essential for adherence o...
Enterohemorrhagic Escherichia coli (EHEC) is a foodborne pathogen causing hemorrhagic colitis and He...
Les Escherichia coli entérohémorragiques (EHEC) sont responsables de toxi-infections alimentaires co...
Enterohaemorrhagic Escherichia coli (EHEC) are bacterial pathogens responsible for life-threatening ...
Enterohaemorrhagic Escherichia coli (EHEC) are bacterial pathogens responsible for life-threatening ...
International audienceShiga-toxin (Stx) is the cardinal virulence factor of enterohemorrhagic Escher...
The locus of enterocyte effacement (LEE) encoded operons (LEE1 - LEE5) enable enterohemorrhagic Esch...
Enterohemorrhagic Escherichia coli (EHEC) is dependent on acid resistance for gastric passage and lo...
Background: Enteropathogenic E. coli (EPEC) and enterohemorrhagic E. coli are important causes of mo...
Enteropathogenic E. coli (EPEC) and enterohemorrhagic E. coli are important causes of morbidity and ...
Enterohaemorrhagic Escherichia coli (EHEC) pathogens represent major difficulties to health as they ...
UNLABELLED: Global regulator of virulence A (GrvA) is a ToxR-family transcriptional regulator that a...
Enterohemorrhagic Escherichia coli (EHEC) is dependent on acid resistance for gastric passage and lo...
UNLABELLED: Global regulator of virulence A (GrvA) is a ToxR-family transcriptional regulator that a...