Phenotypic variation in natural populations results from a combination of genetic effects, environmental effects, and gene-by-environment interactions. Despite the vast amount of genomic data becoming available, many pressing questions remain about the nature of genetic mutations that underlie functional variation. We present the results of combining genome-wide association analysis of 41 different phenotypes in ∼5,000 inbred maize lines to analyze patterns of high-resolution genetic association among of 28.9 million single-nucleotide polymorphisms (SNPs) and ∼800,000 copy-number variants (CNVs). We show that genic and intergenic regions have opposite patterns of enrichment, minor allele frequencies, and effect sizes, implying tradeoffs amo...
BackgroundWith the advances in the high throughput next generation sequencing technologies, genome-w...
In plants, many major regulatory genes that control plant growth and development have been identifie...
Research on domestication informs our understanding of the genetic architectures of important traits...
Phenotypic variation in natural populations results from a combination of genetic effects, environme...
<div><p>Phenotypic variation in natural populations results from a combination of genetic effects, e...
Phenotypic variation in natural populations results from a combination of genetic effects, environme...
Phenotypic variation in natural populations results from a combination of genetic effects, environme...
Genome-Wide Association Studies (GWAS) offer the potential to resolve complex traits to a single gen...
Classical genetic studies have identified many cases of pleiotropy where mutations in individual gen...
Large-scale screens of the maize genome identified 48 genes that show the putative signature of arti...
BACKGROUND:Large-scale screens of the maize genome identified 48 genes that show the putative signat...
Maize genetic diversity has been used to understand the molecular basis of phenotypic variation and ...
Genome-wide association mapping using dense marker sets has identified some nucleotide variants affe...
Selection can result in populations becoming more adapted, yet even in the presence of selection oth...
<div><p>A major goal of maize genomic research is to identify sequence polymorphisms responsible for...
BackgroundWith the advances in the high throughput next generation sequencing technologies, genome-w...
In plants, many major regulatory genes that control plant growth and development have been identifie...
Research on domestication informs our understanding of the genetic architectures of important traits...
Phenotypic variation in natural populations results from a combination of genetic effects, environme...
<div><p>Phenotypic variation in natural populations results from a combination of genetic effects, e...
Phenotypic variation in natural populations results from a combination of genetic effects, environme...
Phenotypic variation in natural populations results from a combination of genetic effects, environme...
Genome-Wide Association Studies (GWAS) offer the potential to resolve complex traits to a single gen...
Classical genetic studies have identified many cases of pleiotropy where mutations in individual gen...
Large-scale screens of the maize genome identified 48 genes that show the putative signature of arti...
BACKGROUND:Large-scale screens of the maize genome identified 48 genes that show the putative signat...
Maize genetic diversity has been used to understand the molecular basis of phenotypic variation and ...
Genome-wide association mapping using dense marker sets has identified some nucleotide variants affe...
Selection can result in populations becoming more adapted, yet even in the presence of selection oth...
<div><p>A major goal of maize genomic research is to identify sequence polymorphisms responsible for...
BackgroundWith the advances in the high throughput next generation sequencing technologies, genome-w...
In plants, many major regulatory genes that control plant growth and development have been identifie...
Research on domestication informs our understanding of the genetic architectures of important traits...