Background: Sequence alignments are the starting point for most evolutionary and comparative analyses. Full genome sequences can be compared to study patterns of within and between species variation. Genome sequence alignments are complex structures containing information such as coordinates, quality scores and synteny structure, which are stored in Multiple Alignment Format (MAF) files. Processing these alignments therefore involves parsing and manipulating typically large MAF files in an efficient way. Results: MafFilter is a command-line driven program written in C++ that enables the processing of genome alignments stored in the Multiple Alignment Format in an efficient and extensible manner. It provides an extensive set of tools which c...
<div><p>In the last decade, the cost of genomic sequencing has been decreasing so much that research...
The amount of data used in phylogenetics has grown explosively in the recent years and many phylogen...
This paper describes a framework and a high-level language toolkit for comparative analysis of genom...
Background: Sequence alignments are the starting point for most evolutionary and comparative analyse...
As the number of available genome sequences from both closely related species and individuals within...
The alignment of biological sequences is crucial for the transfer of annotation from model organisms...
BACKGROUND: Multiple sequence alignment (MSA) is an extremely useful tool for molecular and evolutio...
Abstract Background Constructing alignments and phylogenies for a given locus from large genome sequ...
Background While many bioinformatics tools currently exist for assembling and discovering variants f...
In the last decade, the cost of genomic sequencing has been decreasing so much that researchers all ...
The amount of data used in phylogenetics has grown explosively in the recent years and many phylogen...
A central focus of computational biology is to organize and make use of vast stores of molecular seq...
A central focus of computational biology is to organize and make use of vast stores of molecular seq...
Background: Large multigene sequence alignments have over recent years been increasingly employed f...
MAVID is a multiple alignment program suitable for many large genomic regions. The MAVID webserver a...
<div><p>In the last decade, the cost of genomic sequencing has been decreasing so much that research...
The amount of data used in phylogenetics has grown explosively in the recent years and many phylogen...
This paper describes a framework and a high-level language toolkit for comparative analysis of genom...
Background: Sequence alignments are the starting point for most evolutionary and comparative analyse...
As the number of available genome sequences from both closely related species and individuals within...
The alignment of biological sequences is crucial for the transfer of annotation from model organisms...
BACKGROUND: Multiple sequence alignment (MSA) is an extremely useful tool for molecular and evolutio...
Abstract Background Constructing alignments and phylogenies for a given locus from large genome sequ...
Background While many bioinformatics tools currently exist for assembling and discovering variants f...
In the last decade, the cost of genomic sequencing has been decreasing so much that researchers all ...
The amount of data used in phylogenetics has grown explosively in the recent years and many phylogen...
A central focus of computational biology is to organize and make use of vast stores of molecular seq...
A central focus of computational biology is to organize and make use of vast stores of molecular seq...
Background: Large multigene sequence alignments have over recent years been increasingly employed f...
MAVID is a multiple alignment program suitable for many large genomic regions. The MAVID webserver a...
<div><p>In the last decade, the cost of genomic sequencing has been decreasing so much that research...
The amount of data used in phylogenetics has grown explosively in the recent years and many phylogen...
This paper describes a framework and a high-level language toolkit for comparative analysis of genom...