[[abstract]]Background: Transcription factor binding sites (TFBSs) are crucial in the regulation of gene transcription. Recently, chromatin immunoprecipitation followed by cDNA microarray hybridization (ChIP-chip array) has been used to identify potential regulatory sequences, but the procedure can only map the probable protein-DNA interaction loci within 1-2 kb resolution. To find out the exact binding motifs, it is necessary to build a computational method to examine the ChIP-chip array binding sequences and search for possible motifs representing the transcription factor binding sites.[[fileno]]2030104010015[[department]]電機工程學
BACKGROUND: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mos...
Identifying transcriptional regulatory elements represents a significant challenge in annotating the...
We consider a typical situation, where a researcher has determined one or more clusters of genes co-...
Gene expression is a complex and highly regulated process. Most of the regulation is controlled by s...
ChIP-seq experiments can identify the genome-wide binding site motifs of a transcription factor (TF)...
Coupling chromatin immunoprecipitation (ChIP) with recently developed massively parallel sequencing ...
In the post-genomic era, identification of specific regulatory motifs or transcription factor bindin...
Transcription factor binding sites (TFBSs) are DNA sequences of 6 to 15 base pairs and interaction w...
Understanding the mechanisms that determine the regulation of gene expression is an important and ch...
International audienceEukaryotic genomes contain a variety of structured patterns: repetitive elemen...
Background: Chromatin immunoprecipitation (ChIP) coupled to high-throughput...
Data from ChIP-seq experiments can derive the genome-wide binding specificities of transcription fac...
The network of interactions between transcription factors (TFs) and their regulatory gene targets go...
Background: Binding of transcription factors to transcription factor binding sites (TFBSs) is key to...
<p>Transcriptional regulation is the primary mechanism employed by the cell to ensure coordinated ex...
BACKGROUND: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mos...
Identifying transcriptional regulatory elements represents a significant challenge in annotating the...
We consider a typical situation, where a researcher has determined one or more clusters of genes co-...
Gene expression is a complex and highly regulated process. Most of the regulation is controlled by s...
ChIP-seq experiments can identify the genome-wide binding site motifs of a transcription factor (TF)...
Coupling chromatin immunoprecipitation (ChIP) with recently developed massively parallel sequencing ...
In the post-genomic era, identification of specific regulatory motifs or transcription factor bindin...
Transcription factor binding sites (TFBSs) are DNA sequences of 6 to 15 base pairs and interaction w...
Understanding the mechanisms that determine the regulation of gene expression is an important and ch...
International audienceEukaryotic genomes contain a variety of structured patterns: repetitive elemen...
Background: Chromatin immunoprecipitation (ChIP) coupled to high-throughput...
Data from ChIP-seq experiments can derive the genome-wide binding specificities of transcription fac...
The network of interactions between transcription factors (TFs) and their regulatory gene targets go...
Background: Binding of transcription factors to transcription factor binding sites (TFBSs) is key to...
<p>Transcriptional regulation is the primary mechanism employed by the cell to ensure coordinated ex...
BACKGROUND: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mos...
Identifying transcriptional regulatory elements represents a significant challenge in annotating the...
We consider a typical situation, where a researcher has determined one or more clusters of genes co-...