De novo sequencing is an effective method for identifying unknown peptide sequences from their tandem mass spectra. This unit briefly introduces how this can be done manually. A protocol for using the PEAKS online software for automated de novo sequencing is described. Finally, we show how to use the PEAKS scores to validate the de novo sequencing results
1 Dynamic Programming Approach to Peptide Sequencing 2 Tandem mass spectrometry fragments a large nu...
Dependent on concise, predefined protein sequence databases, traditional search algorithms perform p...
Matching peptide tandem mass spectra to their cognate amino acid sequences in databases is a key ste...
The review describes methods of de novo sequencing of peptides by mass spectrometry. De novo methods...
Peptide sequencing via tandem mass spectrometry (MS/MS) is one of the most powerful tools in proteom...
The impact of mixture spectra deconvolution on the performance of four popular de novo sequencing pr...
Proteomics is the study of proteins, their time- and location-dependent expression profiles, as well...
The Problem: To find the primary sequence of a novel, previously unsequenced peptide from knowledge ...
De novo sequencing of tandem (MS/MS) mass spectra represents the only way to determine the sequence ...
Peptide sequencing plays a fundamental role in proteomics. Tandem mass spectrometry, being sensitive...
UnrestrictedTandem mass spectrometry (MS/MS) has become an important experimental method for high th...
Tandem mass spectrometry (MS/MS) can be used to identify peptides present in a biological sample con...
AbstractThe determination of the amino acid sequence of a peptide from its MS/MS spectrum is an impo...
High resolution mass spectrometry has revolutionized proteomics over the past decade, resulting in t...
In shotgun proteomics, peptide and protein identification is most commonly conducted using database ...
1 Dynamic Programming Approach to Peptide Sequencing 2 Tandem mass spectrometry fragments a large nu...
Dependent on concise, predefined protein sequence databases, traditional search algorithms perform p...
Matching peptide tandem mass spectra to their cognate amino acid sequences in databases is a key ste...
The review describes methods of de novo sequencing of peptides by mass spectrometry. De novo methods...
Peptide sequencing via tandem mass spectrometry (MS/MS) is one of the most powerful tools in proteom...
The impact of mixture spectra deconvolution on the performance of four popular de novo sequencing pr...
Proteomics is the study of proteins, their time- and location-dependent expression profiles, as well...
The Problem: To find the primary sequence of a novel, previously unsequenced peptide from knowledge ...
De novo sequencing of tandem (MS/MS) mass spectra represents the only way to determine the sequence ...
Peptide sequencing plays a fundamental role in proteomics. Tandem mass spectrometry, being sensitive...
UnrestrictedTandem mass spectrometry (MS/MS) has become an important experimental method for high th...
Tandem mass spectrometry (MS/MS) can be used to identify peptides present in a biological sample con...
AbstractThe determination of the amino acid sequence of a peptide from its MS/MS spectrum is an impo...
High resolution mass spectrometry has revolutionized proteomics over the past decade, resulting in t...
In shotgun proteomics, peptide and protein identification is most commonly conducted using database ...
1 Dynamic Programming Approach to Peptide Sequencing 2 Tandem mass spectrometry fragments a large nu...
Dependent on concise, predefined protein sequence databases, traditional search algorithms perform p...
Matching peptide tandem mass spectra to their cognate amino acid sequences in databases is a key ste...
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