This research was concerned with the role of metallothionein (MT) in chemical toxicity mediated by reactive intermediates generated from xenobiotic and oxygen metabolism. Metallothionein(s) are ubiquitous, low molecular weight, cysteine-rich (30% of total amino acids), metal binding proteins. These proteins have been shown to be important in the regulation of essential metal metabolism and in the detoxication of toxic metals. In the present research it was hypothesized that (i) because of its high cysteinyl thiolate concentration, MT is reactive towards intermediates generated from xenobiotic metabolism; and (ii) the metal (Zn, Cu) released from MT concomitant with the inactivation of metal binding sites would influence the modulating role ...
Maintenance of the homeostasis of zinc (Zn) is very important in regulating bodily functions. There ...
Anthropogenic sources of xenobiotic metals with no physiological benefit are increasingly prevalent ...
The growing number of studies on metallothioneins (MTs), cysteine-rich metal-binding proteins, have ...
Metallothioneins (MTs) are sulfhydryl-rich proteins binding essential and non-essential heavy metals...
AbstractLike glutathione or dithiothreitol, metallothionein effects the formation of pancreatic ribo...
Metallothioneins (MTs) are low-molecular-weight cystein-rich metal-binding proteins that are involve...
Metallothionein’s (MTs) are the lower molecular weight (6-7 kDa) proteins that are found to be prese...
One of the most prominent characteristics of metallothionein (MT) is its high cysteine content of 30...
Metallothioneins (MT) are a class of low molecular weight, cysteine rich proteins in almost all livi...
Metallothioneins (MTs) were discovered more than 50 years ago and identified as low-molecular weight...
Free radicals are chemical particles containing one or more unpaired electrons, which may be part of...
none7The effects of radical stress in the biological environment is a very active field of research ...
The metallothioneins (MT) are a class of low molecular weight, cysteine rich proteins found in almos...
The functions, purposes, and roles of metallothioneins have been the subject of speculations since t...
none7The effects of radical stress in the biological environment is a very active field of research ...
Maintenance of the homeostasis of zinc (Zn) is very important in regulating bodily functions. There ...
Anthropogenic sources of xenobiotic metals with no physiological benefit are increasingly prevalent ...
The growing number of studies on metallothioneins (MTs), cysteine-rich metal-binding proteins, have ...
Metallothioneins (MTs) are sulfhydryl-rich proteins binding essential and non-essential heavy metals...
AbstractLike glutathione or dithiothreitol, metallothionein effects the formation of pancreatic ribo...
Metallothioneins (MTs) are low-molecular-weight cystein-rich metal-binding proteins that are involve...
Metallothionein’s (MTs) are the lower molecular weight (6-7 kDa) proteins that are found to be prese...
One of the most prominent characteristics of metallothionein (MT) is its high cysteine content of 30...
Metallothioneins (MT) are a class of low molecular weight, cysteine rich proteins in almost all livi...
Metallothioneins (MTs) were discovered more than 50 years ago and identified as low-molecular weight...
Free radicals are chemical particles containing one or more unpaired electrons, which may be part of...
none7The effects of radical stress in the biological environment is a very active field of research ...
The metallothioneins (MT) are a class of low molecular weight, cysteine rich proteins found in almos...
The functions, purposes, and roles of metallothioneins have been the subject of speculations since t...
none7The effects of radical stress in the biological environment is a very active field of research ...
Maintenance of the homeostasis of zinc (Zn) is very important in regulating bodily functions. There ...
Anthropogenic sources of xenobiotic metals with no physiological benefit are increasingly prevalent ...
The growing number of studies on metallothioneins (MTs), cysteine-rich metal-binding proteins, have ...