Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective study

Applications of CYP450 Testing in the Clinical Setting

Samer, Caroline Flora
Ing Lorenzini, Kuntheavy
Rollason, Victoria
Daali, Youssef
Desmeules, Jules Alexandre

January 2013

Interindividual variability in drug response is a major clinical problem. Polymedication and genetic...

Frequency of the Most Relevant Cytochrome Variants in Patients with Psychiatric Disorders

Slibinskas, Karolis Valentinas

June 2020

Aim of the study: To determine the frequency of CYP2D6, CYP2C9, CYP2C19, VKORC1 variants among the p...

Exploring the role of drug-metabolising enzymes in antidepressant side effects

Hodgson, Karen
Tansey, Katherine
Uher, Rudolf
Dernovšek, Mojca Zvezdana
Mors, Ole
Hauser, Joanna
Souery, Daniel
Maier, Wolfgang
Henigsberg, Neven
Rietschel, Marcella
Placentino, Anna
Craig, Ian W.
Aitchison, Katherine J.
Farmer, Anne E.
Dobson, Richard J. B.
McGuffin, Peter

July 2015

Rationale Cytochrome P450 enzymes are important in the metabolism of antidepressants. The highly pol...

Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective study

Lloret-Linares, Célia
Rollason, Victoria
Lorenzini, Kuntheavy Ing
Samer, Caroline
Daali, Youssef
Gex-Fabry, Marianne
Aubry, Jean-Michel
Desmeules, Jules
Besson, Marie

July 2016

AbstractObjectivesThis retrospective study aimed to assess to what extent an adverse drug reaction (...

Interpreting and Applying CYP450 Genomic Test Results to

Psychotropic Medications
Charles F. Caley

September 2016

The promises of personalized medicine have health care professionals and the public at large in grea...

Therapeutic drug monitoring

Noten, J.B.G.M.
Verhoeven, W.M.A.
Tuinier, S.
Touw, D.

March 1999

The cytochrome P450 iso-enzyme system plays a key role in the biotransformation of many drugs, inclu...

Therapeutische drug monitoring

Noten, J.B.G.M.
Verhoeven, W.M.A.
Tuinier, S.
Touw, D.

March 1999

The cytochrome P450 iso-enzyme system plays a key role in the biotransformation of many drugs, inclu...

Pharmacogenomics in Psychiatry Practice: The Value and the Challenges

Aminah Alchakee
Munazza Ahmed
Leen Eldohaji
Hamid Alhaj
Maha Saber-Ayad

November 2022

The activity of cytochrome P450 enzymes is influenced by genetic and nongenetic factors; hence, the ...

Clinical Applications of CYP Genotyping in Psychiatry

Spina, Edoardo
de Leon, Jose

February 2016

A critical review of the limited available evidence and the authors’ experience and judgment are use...

Physiogenomic analysis of CYP450 drug metabolism correlates dyslipidemia with pharmacogenetic functional status in psychiatric patients.

Ruaño, Gualberto
Villagra, David
Szarek, Bonnie
Windemuth, Andreas
Kocherla, Mohan
Gorowski, Krystyna
Berrezueta, Christopher
Schwartz, Harold I
Goethe, John

August 2011

AIMS: To investigate associations between novel human cytochrome P450 (CYP450) combinatory (multigen...

Cytochrome P-450 2D6 and 2C19 polymorphisms and consumption of care in psychiatric practice

Van Der Baan, Frederieke H.
Gregoor, Jochem G.
Loovers, Harriët M.
Klungel, Olaf H.
Egberts, Toine C.G.
Grobbee, Diederick E.
Knol, Mirjam J.
Van Der Weide, Jan

August 2011

Background: Cytochrome P-450 2D6 (CYP2D6) and 2C19 (CYP2C19) are known to contain functional polymor...

Psychiatry meets pharmacogenetics for the treatment of revolving door patients with psychiatric disorders

Panza, Francesco
Lozupone, Madia
Stella, Eleonora
Lofano, Lucia
Gravina, Carolina
Urbano, Maria
Daniele, Antonio
Logroscino, Giancarlo
Greco, Antonio
Seripa, Davide
BELLOMO, ANTONELLO

January 2016

Introduction: Therapeutic failures (TFs) and adverse drug reactions (ADRs), together with the recurr...

Drugs impact on CYP-450 enzyme family: A pharmacogenetical study of response variation

Kalra, Kapil
Jarmal, Garima
Mishra, Neeti

January 2010

Pharmacogenetics is the study of genetic basis in the individual response to drugs. A thorough knowl...

Frequency and clinical relevance of potential cytochrome P450 drug interactions in a psychiatric patient population – an analysis based on German insurance claims data

Ostermann, Julia K.
Berghoefer, Anne
Andersohn, Frank
Fischer, Felix

January 2016

Background Numerous drugs used in the treatment of psychiatric disorders are substrates of cytochrom...

Pharmacoresistant Severe Mental Health Disorders in Children and Adolescents: Functional Abnormalities of Cytochrome P450 2D6

Susanne Thümmler
Susanne Thümmler
Emmanuelle Dor
Emmanuelle Dor
Renaud David
Graziella Leali
Michele Battista
Michele Battista
Alexia David
Florence Askenazy
Florence Askenazy
Céline Verstuyft
Céline Verstuyft

January 2018

BackgroundSevere mental health disorders in children and adolescents represent a major public health...

Applications of CYP450 Testing in the Clinical Setting

Samer, Caroline Flora
Ing Lorenzini, Kuntheavy
Rollason, Victoria
Daali, Youssef
Desmeules, Jules Alexandre

January 2013

Interindividual variability in drug response is a major clinical problem. Polymedication and genetic...

Frequency of the Most Relevant Cytochrome Variants in Patients with Psychiatric Disorders

Slibinskas, Karolis Valentinas

June 2020

Aim of the study: To determine the frequency of CYP2D6, CYP2C9, CYP2C19, VKORC1 variants among the p...

Exploring the role of drug-metabolising enzymes in antidepressant side effects

Hodgson, Karen
Tansey, Katherine
Uher, Rudolf
Dernovšek, Mojca Zvezdana
Mors, Ole
Hauser, Joanna
Souery, Daniel
Maier, Wolfgang
Henigsberg, Neven
Rietschel, Marcella
Placentino, Anna
Craig, Ian W.
Aitchison, Katherine J.
Farmer, Anne E.
Dobson, Richard J. B.
McGuffin, Peter

July 2015

Rationale Cytochrome P450 enzymes are important in the metabolism of antidepressants. The highly pol...

Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective study

Lloret-Linares, Célia
Rollason, Victoria
Lorenzini, Kuntheavy Ing
Samer, Caroline
Daali, Youssef
Gex-Fabry, Marianne
Aubry, Jean-Michel
Desmeules, Jules
Besson, Marie

July 2016

AbstractObjectivesThis retrospective study aimed to assess to what extent an adverse drug reaction (...

Interpreting and Applying CYP450 Genomic Test Results to

Psychotropic Medications
Charles F. Caley

September 2016

The promises of personalized medicine have health care professionals and the public at large in grea...

Therapeutic drug monitoring

Noten, J.B.G.M.
Verhoeven, W.M.A.
Tuinier, S.
Touw, D.

March 1999

The cytochrome P450 iso-enzyme system plays a key role in the biotransformation of many drugs, inclu...

Therapeutische drug monitoring

Noten, J.B.G.M.
Verhoeven, W.M.A.
Tuinier, S.
Touw, D.

March 1999

The cytochrome P450 iso-enzyme system plays a key role in the biotransformation of many drugs, inclu...

Pharmacogenomics in Psychiatry Practice: The Value and the Challenges

Aminah Alchakee
Munazza Ahmed
Leen Eldohaji
Hamid Alhaj
Maha Saber-Ayad

November 2022

The activity of cytochrome P450 enzymes is influenced by genetic and nongenetic factors; hence, the ...

Clinical Applications of CYP Genotyping in Psychiatry

Spina, Edoardo
de Leon, Jose

February 2016

A critical review of the limited available evidence and the authors’ experience and judgment are use...

Physiogenomic analysis of CYP450 drug metabolism correlates dyslipidemia with pharmacogenetic functional status in psychiatric patients.

Ruaño, Gualberto
Villagra, David
Szarek, Bonnie
Windemuth, Andreas
Kocherla, Mohan
Gorowski, Krystyna
Berrezueta, Christopher
Schwartz, Harold I
Goethe, John

August 2011

AIMS: To investigate associations between novel human cytochrome P450 (CYP450) combinatory (multigen...

Cytochrome P-450 2D6 and 2C19 polymorphisms and consumption of care in psychiatric practice

Van Der Baan, Frederieke H.
Gregoor, Jochem G.
Loovers, Harriët M.
Klungel, Olaf H.
Egberts, Toine C.G.
Grobbee, Diederick E.
Knol, Mirjam J.
Van Der Weide, Jan

August 2011

Background: Cytochrome P-450 2D6 (CYP2D6) and 2C19 (CYP2C19) are known to contain functional polymor...

Psychiatry meets pharmacogenetics for the treatment of revolving door patients with psychiatric disorders

Panza, Francesco
Lozupone, Madia
Stella, Eleonora
Lofano, Lucia
Gravina, Carolina
Urbano, Maria
Daniele, Antonio
Logroscino, Giancarlo
Greco, Antonio
Seripa, Davide
BELLOMO, ANTONELLO

January 2016

Introduction: Therapeutic failures (TFs) and adverse drug reactions (ADRs), together with the recurr...

Drugs impact on CYP-450 enzyme family: A pharmacogenetical study of response variation

Kalra, Kapil
Jarmal, Garima
Mishra, Neeti

January 2010

Pharmacogenetics is the study of genetic basis in the individual response to drugs. A thorough knowl...

Frequency and clinical relevance of potential cytochrome P450 drug interactions in a psychiatric patient population – an analysis based on German insurance claims data

Ostermann, Julia K.
Berghoefer, Anne
Andersohn, Frank
Fischer, Felix

January 2016

Background Numerous drugs used in the treatment of psychiatric disorders are substrates of cytochrom...

Pharmacoresistant Severe Mental Health Disorders in Children and Adolescents: Functional Abnormalities of Cytochrome P450 2D6

Susanne Thümmler
Susanne Thümmler
Emmanuelle Dor
Emmanuelle Dor
Renaud David
Graziella Leali
Michele Battista
Michele Battista
Alexia David
Florence Askenazy
Florence Askenazy
Céline Verstuyft
Céline Verstuyft

January 2018

BackgroundSevere mental health disorders in children and adolescents represent a major public health...

Applications of CYP450 Testing in the Clinical Setting

Samer, Caroline Flora
Ing Lorenzini, Kuntheavy
Rollason, Victoria
Daali, Youssef
Desmeules, Jules Alexandre

January 2013

Interindividual variability in drug response is a major clinical problem. Polymedication and genetic...

Frequency of the Most Relevant Cytochrome Variants in Patients with Psychiatric Disorders

Slibinskas, Karolis Valentinas

June 2020

Aim of the study: To determine the frequency of CYP2D6, CYP2C9, CYP2C19, VKORC1 variants among the p...

Exploring the role of drug-metabolising enzymes in antidepressant side effects

Hodgson, Karen
Tansey, Katherine
Uher, Rudolf
Dernovšek, Mojca Zvezdana
Mors, Ole
Hauser, Joanna
Souery, Daniel
Maier, Wolfgang
Henigsberg, Neven
Rietschel, Marcella
Placentino, Anna
Craig, Ian W.
Aitchison, Katherine J.
Farmer, Anne E.
Dobson, Richard J. B.
McGuffin, Peter

July 2015

Rationale Cytochrome P450 enzymes are important in the metabolism of antidepressants. The highly pol...

Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective study

Abstract

Extracted data

Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective study

Abstract

Extracted data

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