The Human Autoantibody Response to Apolipoprotein A-I Is Focused on the C-Terminal Helix: A New Rationale for Diagnosis and Treatment of Cardiovascular Disease?
- Pagano, Sabrina
- Gaertner, Hubert François
- Cerini, Fabrice
- Mannic, Tiphaine
- Satta, Nathalie
- Teixeira, Priscila Camillo
- Cutler, Paul
- Mach, François
- Vuilleumier, Nicolas
- Hartley, Oliver
Publication date
January 2015
DOI Publisher
Public Library of Science (PLoS) ISSN
1932-6203 Citation count (estimate)
7Abstract
Cardiovascular disease (CVD) is the leading cause of death worldwide and new approaches for both diagnosis and treatment are required. Autoantibodies directed against apolipoprotein A-I (ApoA-I) represent promising biomarkers for use in risk stratification of CVD and may also play a direct role in pathogenesis
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