Methylation of Serotonin Receptor 3a in ADHD, Borderline Personality, and Bipolar Disorders: Link with Severity of the Disorders and Childhood Maltreatment
- Perroud, Nader Ali
- Zewdie Wondimu, Seblewongel
- Stenz, Ludwig
- Adouan, Wafae
- Bavamian Suter, Sabine
- Prada, Paco Boris
- Nicastro, Rosetta
- Hasler, Roland
- Nallet, Audrey
- Piguet, Camille Marie
- Giacobino, Ariane
- Aubry, Jean-Michel
- Dayer, Alexandre
Publication date
January 2016
DOI Publisher
Wiley ISSN
1091-4269 Citation count (estimate)
24Abstract
Serotonin 3A receptor (5-HT3A R) is associated at the genetic and epigenetic levels with a variety of psychiatric disorders and interacts with early-life stress such as childhood maltreatment. We studied the impact of childhood maltreatment on the methylation status of the 5-HT3A R and its association with clinical severity outcomes in relation with a functional genetic polymorphism
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