Lower vitamin D levels are associated with higher systemic lupus erythematosus activity, but not predictive of disease flare-up
- Schoindre, Yoland
- Jallouli, Moez
- Tanguy, Marie-Laure
- Ghillani, Pascale
- Galicier, Lionel
- Aumaître, Olivier
- Francès, Camille
- Le Guern, Véronique
- Lioté, Frédéric
- Smail, Amar
- Limal, Nicolas
- Perard, Laurent
- Desmurs-Clavel, Hélène
- Le Thi Huong, Du
- Asli, Bouchra
- Kahn, Jean-Emmanuel
- Sailler, Laurent
- Ackermann, Félix
- Papo, Thomas
- Sacré, Karim
- Fain, Olivier
- Stirnemann, Jérôme
- Cacoub, Patrice
- Leroux, Gaëlle
- Cohen-Bittan, Judith
- Hulot, Jean-Sébastien
- Lechat, Philippe
- Musset, Lucile
- Piette, Jean-Charles
- Amoura, Zahir
- Souberbielle, Jean-Claude
- Costedoat-Chalumeau, Nathalie
Publication date
January 2014
DOI Publisher
BMJ ISSN
2053-8790 Citation count (estimate)
21Abstract
Growing evidence suggests that vitamin D plays a key role in the pathogenesis and progression of autoimmune diseases, including systemic lupus erythematosus (SLE). Recent studies have found an association between lower serum 25-hydroxyvitamin D (25(OH)D) levels and higher SLE activity. We studied the relationship between 25(OH)D levels and Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) score, and we assessed for the first time the role of vitamin D in predicting SLE flare-ups
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