The mechanisms responsible for the development of a pyogenic infection (most commonly due to staphylococci) in the vicinity of an implanted foreign body have been studied recently by several investigators. Thus, we have been able to demonstrate that the phagocytic function of residential polymorphonuclear leukocytes (PMN) is deficient in the presence of a foreign body. Others have shown that in the presence of foreign surfaces, microorganisms produce extracellular amorphous material, the pathogenic role of which is still to be defined. In the present study we use a novel assay system to demonstrate that Staphylococcus aureus Wood 46, after attachment to polymethylmethacrylate (PMMA), shows increased resistance to the phagocytic-bactericidal...
<p>Macrophages were treated with 10 or 100 µg/ml poly(I) or its negative control chondroitin sulfate...
Foreign bodies made of polymethylmethacrylate coverslips were implanted subcutaneously into guinea p...
<p>Adherent GM-MФ were treated with 10 µg/ml poly(I) or its negative control chondroitin sulfate pri...
Using a previously developed guinea pig model of foreign body infection, we examined ultrastructural...
Using a previously developed guinea pig model of foreign body infection, we examined ultrastructural...
The genus Staphylococcus contains common pathogens of both humans and animals. In this study the ph...
Recent data suggest that fibronectin may favor Staphylococcus aureus infection by promoting attachme...
Biomaterial-associated-infection causes failure of biomaterial implants. Many new biomaterials have ...
Bacterial biofilms can increase the pathogenicity of infection and constitute a major problem in mod...
Recent data suggest that fibronectin may favor Staphylococcus aureus infection by promoting attachme...
Virulent strains of staphylococci are known to resist phagocytic destruction better than avirulent s...
Alveolar macrophages (AMs) can phagocytose unopsonized pathogens such as S. aureus via innate immune...
Foreign bodies made of polymethylmethacrylate coverslips were implanted subcutaneously into guinea p...
Pathogenicity of methicillin-resistant (MR) strains of S. aureus is difficult to determine from clin...
An animal model involving the subcutaneous implantation of tissue cages into guinea pigs and subsequ...
<p>Macrophages were treated with 10 or 100 µg/ml poly(I) or its negative control chondroitin sulfate...
Foreign bodies made of polymethylmethacrylate coverslips were implanted subcutaneously into guinea p...
<p>Adherent GM-MФ were treated with 10 µg/ml poly(I) or its negative control chondroitin sulfate pri...
Using a previously developed guinea pig model of foreign body infection, we examined ultrastructural...
Using a previously developed guinea pig model of foreign body infection, we examined ultrastructural...
The genus Staphylococcus contains common pathogens of both humans and animals. In this study the ph...
Recent data suggest that fibronectin may favor Staphylococcus aureus infection by promoting attachme...
Biomaterial-associated-infection causes failure of biomaterial implants. Many new biomaterials have ...
Bacterial biofilms can increase the pathogenicity of infection and constitute a major problem in mod...
Recent data suggest that fibronectin may favor Staphylococcus aureus infection by promoting attachme...
Virulent strains of staphylococci are known to resist phagocytic destruction better than avirulent s...
Alveolar macrophages (AMs) can phagocytose unopsonized pathogens such as S. aureus via innate immune...
Foreign bodies made of polymethylmethacrylate coverslips were implanted subcutaneously into guinea p...
Pathogenicity of methicillin-resistant (MR) strains of S. aureus is difficult to determine from clin...
An animal model involving the subcutaneous implantation of tissue cages into guinea pigs and subsequ...
<p>Macrophages were treated with 10 or 100 µg/ml poly(I) or its negative control chondroitin sulfate...
Foreign bodies made of polymethylmethacrylate coverslips were implanted subcutaneously into guinea p...
<p>Adherent GM-MФ were treated with 10 µg/ml poly(I) or its negative control chondroitin sulfate pri...