Neuropeptide Y (NPY) is a highly potent orexigenic substance that is also known to modulate gonadotropin secretion. Five receptor subtypes for NPY have been identified, and a potent antagonist for the receptor subtype 1 (Y1), 1229U91, also known as GW1229 or GR231118, has been described. Subsequently, 1229U91 was also shown to represent a highly potent agonist for the Y4 receptor subtype. Very unexpectedly, intracerebroventricular administration of 1229U91 elicited an intense, dose-dependent surge of both luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in intact male rats that lasted for 6 h. Such stimulation was absent when a potent gonadotropin-releasing hormone antagonist was administered systemically, suggesting that 122...
Neuropeptide Y (NPY) plays a major role in the regulation of food intake, regulation of homeostasis,...
Kisspeptin, neurokinin B (NKB) and dynorphin A (Dyn) are coexpressed within KNDy neurons that projec...
We have previously reported that neuropeptide-Y (NPY) stimulates GH and gonadotropin-II (GtH-II) rel...
Neuropeptide Y (NPY) is a highly potent orexigenic substance that is also known to modulate gonadotr...
A number of studies have indicated that neuropeptide Y (NPY) is a central regulator of the gonadotro...
To test the hypothesis that neuropeptide Y (NPY) is involved in the regulation of the estrogen/proge...
We showed previously that neuropeptide Y1 receptor (Y1R) expression is increased in the hypothalamus...
The factors that influence Leydig cell activity currently include peptides such as neuropeptide Y (N...
Pubertal development results from the coordinate secretion of gonadotropin-releasing hormone (GnRH) ...
Neuropeptide Y (NPY) is an important central and peripheral modulator of neural and endocrine functi...
Neuropeptide Y (NPY) stimulates the release of GnRH in an es-trogen (E2)-dependent manner, which is ...
The aim of this work was to investigate whether the expression of leptin receptors (OBR) in the hypo...
The rat glucocorticoid induced receptor (rGIR) is an orphan G protein-coupled receptor awaiting phar...
We investigated the participation of neuropeptide Y-Y1 receptors within the medial preoptic area in ...
Leptin may act as a negative feedback signal to the brain in the control of appetite through suppres...
Neuropeptide Y (NPY) plays a major role in the regulation of food intake, regulation of homeostasis,...
Kisspeptin, neurokinin B (NKB) and dynorphin A (Dyn) are coexpressed within KNDy neurons that projec...
We have previously reported that neuropeptide-Y (NPY) stimulates GH and gonadotropin-II (GtH-II) rel...
Neuropeptide Y (NPY) is a highly potent orexigenic substance that is also known to modulate gonadotr...
A number of studies have indicated that neuropeptide Y (NPY) is a central regulator of the gonadotro...
To test the hypothesis that neuropeptide Y (NPY) is involved in the regulation of the estrogen/proge...
We showed previously that neuropeptide Y1 receptor (Y1R) expression is increased in the hypothalamus...
The factors that influence Leydig cell activity currently include peptides such as neuropeptide Y (N...
Pubertal development results from the coordinate secretion of gonadotropin-releasing hormone (GnRH) ...
Neuropeptide Y (NPY) is an important central and peripheral modulator of neural and endocrine functi...
Neuropeptide Y (NPY) stimulates the release of GnRH in an es-trogen (E2)-dependent manner, which is ...
The aim of this work was to investigate whether the expression of leptin receptors (OBR) in the hypo...
The rat glucocorticoid induced receptor (rGIR) is an orphan G protein-coupled receptor awaiting phar...
We investigated the participation of neuropeptide Y-Y1 receptors within the medial preoptic area in ...
Leptin may act as a negative feedback signal to the brain in the control of appetite through suppres...
Neuropeptide Y (NPY) plays a major role in the regulation of food intake, regulation of homeostasis,...
Kisspeptin, neurokinin B (NKB) and dynorphin A (Dyn) are coexpressed within KNDy neurons that projec...
We have previously reported that neuropeptide-Y (NPY) stimulates GH and gonadotropin-II (GtH-II) rel...