Correlates of self-reported nonadherence to antiretroviral therapy in HIV-infected patients: the Swiss HIV Cohort Study
- Glass, T. R.
- De Geest, Sabina
- Weber, Rainer
- Vernazza, P. L.
- Rickenbach, Martin
- Furrer, Hansjakob
- Bernasconi, Enos
- Cavassini, Matthias
- Hirschel, Bernard
- Battegay, Manuel
- Bucher, H. C.
DOIAbstract
BACKGROUND: Adherence is one of the most crucial issues in the clinical management of HIV-infected patients receiving antiretroviral therapy (ART). METHODS: A 2-item adherence questionnaire was introduced into the Swiss HIV Cohort Study in July 2003. All 3607 eligible patients were on ART for > or =6 months and their current regimen for > or =1 month. Three definitions of nonadherence were considered: missing > or =1 dose, missing > or =2 doses, and taking or =1 dose, 14.9% missed > or =2 doses, and 7.1% took <95% of doses in the previous 4 weeks. The rate of drug holidays was 5.8%. Whether using more or less conservative definitions of nonadherence, younger age, living alone, number of previous regimens, and boosted protease inhibitor reg...
Add to ORKG