Protective effect of vitamin B6 against carbon tetrachloride induced hepatotoxicity in male rats: Effect on liver enzymes, glucose, total protein and insulin hormone.

The current study revealed that the CCl4 has harmful effects on the liver function which led to a significant increase of activities of AST, ALT, ALP and LDH in the four periods of the experiment, especially in the first two periods (two weeks and the second four weeks). The current study revealed that CCl4 led to a significant increase (p<0.05) in the level of glucose, and decrease in the level of the total protein of the plasma. Vitamin B6 has a protection action against the harmful effects of the CCl4 especially during the first two periods, whereas the harmful effect was significantly less (p