Investigation of the thermal and tissue injury behaviour in microwave thermal therapy using a porcine kidney model
- He, X
- McGee, S
- Coad, J E
- Schmidlin, Franz
- Iaizzo, P A
- Swanlund, D J
- Kluge, S
- Rudie, E
- Bischof, J C
DOIAbstract
Minimally invasive microwave thermal therapies are being developed for the treatment of small renal cell carcinomas (RCC, d<3 cm). This study assessed the thermal history and corresponding tissue injury patterns resulting from microwave treatment of the porcine renal cortex. Three groups of kidneys were evaluated: (1) in vitro treated, (2) in vivo with 2-h post-treatment perfusion (acute) and (3) in vivo with 7-day post-treatment perfusion (chronic). The kidneys were treated with an interstitial water-cooled microwave probe (Urologix, Plymouth, MN) that created a lesion centered in the renal cortex (50 W for 10 min). The thermal histories were recorded at 0.5 cm radial intervals from the probe axis for correlation with the histologic cellul...
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