The zinc finger protein ZBTB20 regulates transcription of fructose-1,6-bisphosphatase 1 and β cell function in mice
- Zhang, Ye
- Xie, Zhifang
- Zhou, Luting
- Li, Ling
- Zhang, Hai
- Zhou, Guangdi
- Ma, Xianhua
- Herrera, Pedro Luis
- Liu, Zhimin
- Grusby, Michael J
- Zhang, Weiping J
Publication date
January 2012
DOI Publisher
Elsevier BV ISSN
0016-5085 Citation count (estimate)
15Abstract
Fructose-1,6-bisphosphatase (FBP)-1 is a gluconeogenic enzyme that regulates glucose metabolism and insulin secretion in β cells, but little is known about how its transcription is controlled. The zinc finger protein ZBTB20 regulates glucose homeostasis, so we investigated its effects on expression of FBP-1
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