Tissue engineering was born from the belief that primary cells could be isolated from a patient, expanded in vitro and seeded onto a substrate that could be grafted back into the patient (Yang et a/, 2001) providing a biological alternative to transplantations and prosthesis. There are three main components in tissue engineering, scaffolds, cells and signalling mechanisms that make up the tissue engineering triad. This thesis focuses on the interplay between cell behaviour and scaffold structural properties. Recent studies from our laboratory have developed novel freeze-drying techniques to vary the structure of collagen-glycosaminoglycan (GAG) scaffolds producing scaffolds with mean pores ranging from 85 pm - 325 pm (Haugh et a/, 2010). Th...
Cells sense and respond to scaffold pore geometry and mechanical stimuli. Many fabrication methods u...
Although many bone substitutes have been designed and produced, the development of bone tissue engin...
Recent investigations into micro-architecture of scaffolds has revealed that mean pore sizes are cel...
Tissue engineering was born from the belief that primary cells could be isolated from a patient, exp...
Tissue engineering was born from the belief that primary cells could be isolated from a patient, exp...
In the literature there are conflicting reports on the optimal scaffold mean pore size required for ...
Collagen-glycosaminoglycan (GAG) scaffolds were initially designed for use in skin regeneration and ...
Currently, there exists a need to develop new bone graft substitutes as an alternative to convention...
Recent investigations into micro-architecture of scaffolds has revealed that mean pore sizes are cel...
The biological activity of scaffolds used in tissue engineering applications hypothetically depends ...
Cells sense and respond to scaffold pore geometry and mechanical stimuli. Many fabrication methods u...
Cells sense and respond to scaffold pore geometry and mechanical stimuli. Many fabrication methods u...
Cells sense and respond to scaffold pore geometry and mechanical stimuli. Many fabrication methods u...
Cells sense and respond to scaffold pore geometry and mechanical stimuli. Many fabrication methods u...
Cells sense and respond to scaffold pore geometry and mechanical stimuli. Many fabrication methods u...
Cells sense and respond to scaffold pore geometry and mechanical stimuli. Many fabrication methods u...
Although many bone substitutes have been designed and produced, the development of bone tissue engin...
Recent investigations into micro-architecture of scaffolds has revealed that mean pore sizes are cel...
Tissue engineering was born from the belief that primary cells could be isolated from a patient, exp...
Tissue engineering was born from the belief that primary cells could be isolated from a patient, exp...
In the literature there are conflicting reports on the optimal scaffold mean pore size required for ...
Collagen-glycosaminoglycan (GAG) scaffolds were initially designed for use in skin regeneration and ...
Currently, there exists a need to develop new bone graft substitutes as an alternative to convention...
Recent investigations into micro-architecture of scaffolds has revealed that mean pore sizes are cel...
The biological activity of scaffolds used in tissue engineering applications hypothetically depends ...
Cells sense and respond to scaffold pore geometry and mechanical stimuli. Many fabrication methods u...
Cells sense and respond to scaffold pore geometry and mechanical stimuli. Many fabrication methods u...
Cells sense and respond to scaffold pore geometry and mechanical stimuli. Many fabrication methods u...
Cells sense and respond to scaffold pore geometry and mechanical stimuli. Many fabrication methods u...
Cells sense and respond to scaffold pore geometry and mechanical stimuli. Many fabrication methods u...
Cells sense and respond to scaffold pore geometry and mechanical stimuli. Many fabrication methods u...
Although many bone substitutes have been designed and produced, the development of bone tissue engin...
Recent investigations into micro-architecture of scaffolds has revealed that mean pore sizes are cel...