Add to ORKGWe have previously shown that, in normal human airway tissue, localization of the cystic fibrosis transmembrane conductance regulator (CFTR) can be affected by epithelial maturation, polarity, and differentiation and that CFTR trafficking and apical localization depend on the integrity of the airway epithelium. In this study, we addressed the question of whether the three-dimensional (3-D) organization of adult human airway epithelial cells in suspension culture under rotation, leading to spheroid-like structures, could mimic the in vivo phenomenon of differentiation and polarization. The kinetics of the differentiation, polarity, and formation of the CFTR-ZO-1-ezrin complex was analyzed by transmission, scanning, and immunofluorescence mic...
We examined the activity of ΔF508 cystic fibrosis transmembrane conductance regulator (CFTR) stably ...
Physical stimulation of airway surfaces evokes liquid secretion, but the events that mediate this vi...
Cystic fibrosis (CF) is a multi-organ autosomal recessive disease of fluid-transporting epithelia, d...
We have previously shown that, in normal human airway tissue, localization of the cystic fibrosis tr...
Cystic fibrosis, an autosomal recessive disorder caused by a mutation in a gene encoding the cystic ...
Cystic fibrosis, an autosomal recessive disorder caused by a mutation in a gene encoding the cystic ...
The poor ability of respiratory epithelial cells to proliferate and differentiate in vitro into a ps...
Cystic fibrosis (CF) is the most common lethal autosomal recessive genetic disorder that affects the...
Cystic Fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR), a ...
In cystic fibrosis, the respiratory epithelium is the target tissue of both the genetic abnormality ...
The airway epithelium contains ionocytes, a rare cell type with high expression of Forkhead Box I1 (...
The functions of epithelial tissues are dictated by the types, abundance and distribution of the dif...
Dysfunction of CFTR in cystic fibrosis (CF) airway epithelium perturbs the normal regulation of ion ...
(IF : 4,608)International audienceCystic fibrosis is caused by mutations in the cystic fibrosis tran...
Cystic fibrosis (CF) at an advanced stage of the disease is characterized by airway epithelial injur...
We examined the activity of ΔF508 cystic fibrosis transmembrane conductance regulator (CFTR) stably ...
Physical stimulation of airway surfaces evokes liquid secretion, but the events that mediate this vi...
Cystic fibrosis (CF) is a multi-organ autosomal recessive disease of fluid-transporting epithelia, d...
We have previously shown that, in normal human airway tissue, localization of the cystic fibrosis tr...
Cystic fibrosis, an autosomal recessive disorder caused by a mutation in a gene encoding the cystic ...
Cystic fibrosis, an autosomal recessive disorder caused by a mutation in a gene encoding the cystic ...
The poor ability of respiratory epithelial cells to proliferate and differentiate in vitro into a ps...
Cystic fibrosis (CF) is the most common lethal autosomal recessive genetic disorder that affects the...
Cystic Fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR), a ...
In cystic fibrosis, the respiratory epithelium is the target tissue of both the genetic abnormality ...
The airway epithelium contains ionocytes, a rare cell type with high expression of Forkhead Box I1 (...
The functions of epithelial tissues are dictated by the types, abundance and distribution of the dif...
Dysfunction of CFTR in cystic fibrosis (CF) airway epithelium perturbs the normal regulation of ion ...
(IF : 4,608)International audienceCystic fibrosis is caused by mutations in the cystic fibrosis tran...
Cystic fibrosis (CF) at an advanced stage of the disease is characterized by airway epithelial injur...
We examined the activity of ΔF508 cystic fibrosis transmembrane conductance regulator (CFTR) stably ...
Physical stimulation of airway surfaces evokes liquid secretion, but the events that mediate this vi...
Cystic fibrosis (CF) is a multi-organ autosomal recessive disease of fluid-transporting epithelia, d...