BACKGROUND: Diseases distributions are not the same all over France. As diet is an important determinant of health it is essential to determine whether there was still a diversity in food habits across French regions. AIM OF THE STUDY: We examined regional differences in dietary habits and nutrient intakes among French women born between 1925 and 1950 participants in the "Etude Epid?ologique aupr?des femmes de l'Education Nationale" (E3N) cohort. METHODS: Data were extracted from self-administered dietary history questionnaires completed by 73024 highly educated, middle-aged women between 1993 and 1995. Canonical and cluster analyses were used to identify contiguous areas of homogeneous dietary habits spanning two or more of the 20 French r...