Rheumatoid arthritis (RA) is a complex polygenic inflammatory disease associated with accelerated atherosclerosis and increased risk of cardiovascular (CV) disease. Previous genome-wide association studies have described SMAD3 rs17228212 polymorphism as an important signal associated with CV events. The aim of the present study was to evaluate for the first time the relationship between this gene polymorphism and the susceptibility to CV manifestations and its potential association with the presence of subclinical atherosclerosis assessed by the evaluation of carotid intima-media thickness (cIMT) in patients with RA.Methods:One thousand eight hundred and ninety-seven patients fulfilling classification criteria for RA were genotyped for SMAD...
Carotid Intima-media thickness (CIMT) and plaque are well established markers of subclinical atheros...
Objective: rheumatoid arthritis (RA) is a chronic inflammatory disease associated with increased car...
A genetic component influences the development of atherosclerosis in the general population and also...
Rheumatoid arthritis (RA) is a complex polygenic inflammatory disease associated with accelerated at...
Rheumatoid arthritis (RA) is a complex polygenic inflammatory disease associated with accelerated at...
A genetic component influences the development of atherosclerosis in the general population and als...
A genetic component influences the development of atherosclerosis in the general population and also...
rs17228212 gene polymorphism through TaqMan genotyping assay. Also, subclinical atherosclerosis det...
To investigate the genetic background influencing the development of cardiovascular (CV) disease in ...
OBJECTIVES: To determine whether the interleukin-33 (IL-33)-interleukin-1 receptor like 1 (IL-1RL1) ...
Rheumatoid arthritis (RA) is a complex polygenic inflammatory disease associated with accelerated at...
OBJECTIVE: To investigate the genetic background influencing the development of cardiovascular (CV)...
A genetic component influences the development of atherosclerosis in the general population and also...
To investigate the genetic background influencing the development of cardiovascular (CV) disease in ...
Background and aims: Little is known about specific genetic determinants of carotid-intima-media thi...
Carotid Intima-media thickness (CIMT) and plaque are well established markers of subclinical atheros...
Objective: rheumatoid arthritis (RA) is a chronic inflammatory disease associated with increased car...
A genetic component influences the development of atherosclerosis in the general population and also...
Rheumatoid arthritis (RA) is a complex polygenic inflammatory disease associated with accelerated at...
Rheumatoid arthritis (RA) is a complex polygenic inflammatory disease associated with accelerated at...
A genetic component influences the development of atherosclerosis in the general population and als...
A genetic component influences the development of atherosclerosis in the general population and also...
rs17228212 gene polymorphism through TaqMan genotyping assay. Also, subclinical atherosclerosis det...
To investigate the genetic background influencing the development of cardiovascular (CV) disease in ...
OBJECTIVES: To determine whether the interleukin-33 (IL-33)-interleukin-1 receptor like 1 (IL-1RL1) ...
Rheumatoid arthritis (RA) is a complex polygenic inflammatory disease associated with accelerated at...
OBJECTIVE: To investigate the genetic background influencing the development of cardiovascular (CV)...
A genetic component influences the development of atherosclerosis in the general population and also...
To investigate the genetic background influencing the development of cardiovascular (CV) disease in ...
Background and aims: Little is known about specific genetic determinants of carotid-intima-media thi...
Carotid Intima-media thickness (CIMT) and plaque are well established markers of subclinical atheros...
Objective: rheumatoid arthritis (RA) is a chronic inflammatory disease associated with increased car...
A genetic component influences the development of atherosclerosis in the general population and also...