Diffuse large B-cell lymphoma can be classified by gene expression profiling into germinal center and activated Bcell subtypes with different prognoses after rituximab-CHOP. The importance of previously recognized prognostic markers, such as Bcl-2 protein expression and BCL2 gene abnormalities, has been questioned in the new therapeutic era. We analyzed Bcl-2 protein expression, and BCL2 and MYC gene abnormalities by interphase fluorescence in situ hybridization in 327 patients with de novo disease treated with rituximab-CHOP. Isolated BCL2 and MYC rearrangements were not predictive of outcome in our patients as a whole, but only in those with the germinal center subtype of lymphoma. The prognostic relevance of isolated MYC rearrangements w...
This journal issue is proceedings of ASH Conference 2012Open Access JournalOral Sessions - 622. Non-...
AIMS: Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease with various genetic alterati...
Purpose Outcome of diffuse large B-cell lymphoma (DLBCL) with a germinal center B-cell (GCB) express...
Diffuse large B-cell lymphoma can be classified by gene expression profiling into germinal center an...
Diffuse large B-cell lymphoma can be classified by gene expression profiling into germinal center an...
Diffuse large B-cell lymphoma can be classified by gene expression profiling into germinal center an...
Diffuse large B-cell lymphoma can be classified by gene expression profiling into germinal center an...
Oral Sessions - 622. Non-Hodgkin Lymphoma - Biology, excluding Therapy: Clinical Determinants and Mi...
Diffuse large B-cell lymphoma (DLBCL) is stratified into prognostically favorable germinal center B-...
Diffuse large B-cell lymphoma (DLBCL) is stratified into prognostically favorable germinal center B-...
Diffuse large B-cell lymphoma (DLBCL) is stratified into prognostically favorable germinal center B-...
Diffuse large B-cell lymphoma (DLBCL) is stratified into prognostically favorable germinal center B-...
AIMS: Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease with various genetic alterati...
PurposeOutcome of diffuse large B-cell lymphoma (DLBCL) with a germinal center B-cell (GCB) expressi...
PurposeOutcome of diffuse large B-cell lymphoma (DLBCL) with a germinal center B-cell (GCB) expressi...
This journal issue is proceedings of ASH Conference 2012Open Access JournalOral Sessions - 622. Non-...
AIMS: Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease with various genetic alterati...
Purpose Outcome of diffuse large B-cell lymphoma (DLBCL) with a germinal center B-cell (GCB) express...
Diffuse large B-cell lymphoma can be classified by gene expression profiling into germinal center an...
Diffuse large B-cell lymphoma can be classified by gene expression profiling into germinal center an...
Diffuse large B-cell lymphoma can be classified by gene expression profiling into germinal center an...
Diffuse large B-cell lymphoma can be classified by gene expression profiling into germinal center an...
Oral Sessions - 622. Non-Hodgkin Lymphoma - Biology, excluding Therapy: Clinical Determinants and Mi...
Diffuse large B-cell lymphoma (DLBCL) is stratified into prognostically favorable germinal center B-...
Diffuse large B-cell lymphoma (DLBCL) is stratified into prognostically favorable germinal center B-...
Diffuse large B-cell lymphoma (DLBCL) is stratified into prognostically favorable germinal center B-...
Diffuse large B-cell lymphoma (DLBCL) is stratified into prognostically favorable germinal center B-...
AIMS: Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease with various genetic alterati...
PurposeOutcome of diffuse large B-cell lymphoma (DLBCL) with a germinal center B-cell (GCB) expressi...
PurposeOutcome of diffuse large B-cell lymphoma (DLBCL) with a germinal center B-cell (GCB) expressi...
This journal issue is proceedings of ASH Conference 2012Open Access JournalOral Sessions - 622. Non-...
AIMS: Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease with various genetic alterati...
Purpose Outcome of diffuse large B-cell lymphoma (DLBCL) with a germinal center B-cell (GCB) express...