Additional description of methods, including the impact of cell geometry on equations and parameters, and estimation of the values of receptor dimerization rate constants. Includes sources for justification of key parameters [6, 37–40]. (PDF)</p
Short title: Algal receptor-like kinase for sexual reproduction Subject areas (primary): cell-cell i...
<p>The second scenario was applied, in which the total number of receptor A was fixed and the total ...
<p>(A). Dimerization curves. Black circles: Averaged dimeric fractions measured for the wild-type co...
Note that these base parameters (in units of molecules-1.μm2.s-1) are adjusted to units of molecules...
Comparison of techniques for the analysis of cell-surface receptor-ligand interactions.</p
Mechanistic models of G-protein coupled receptor (GPCR) signaling are used to gain insight into how ...
<p><b>a</b> The dimerization propensity is given as the relative number of dimers formed per microse...
Many G protein-coupled receptors have been shown to exist as oligomers, but the oligomerization stat...
Also provided in the appendix are the model parameters used in the Hodgkin and Huxley formulation of...
<p>Concentration responses of L, RS, LRS, and LRI to step changes in the ligand input rate. Two inpu...
Accurate ranking of efficacies and potencies of agonists is essential in the discovery of new select...
<p>Concentration-time profiles of ligand computed at medium cell density () for nM. These profiles ...
Many cellular reactions involve a reactant in solution binding to or dissociating from a reactant at...
<p>Ligand profiles computed as a function of distance at high cell density () and nM for s (A) and...
<p><b>A</b>) Species included in the mathematical model. The model consists of two distinct ligands,...
Short title: Algal receptor-like kinase for sexual reproduction Subject areas (primary): cell-cell i...
<p>The second scenario was applied, in which the total number of receptor A was fixed and the total ...
<p>(A). Dimerization curves. Black circles: Averaged dimeric fractions measured for the wild-type co...
Note that these base parameters (in units of molecules-1.μm2.s-1) are adjusted to units of molecules...
Comparison of techniques for the analysis of cell-surface receptor-ligand interactions.</p
Mechanistic models of G-protein coupled receptor (GPCR) signaling are used to gain insight into how ...
<p><b>a</b> The dimerization propensity is given as the relative number of dimers formed per microse...
Many G protein-coupled receptors have been shown to exist as oligomers, but the oligomerization stat...
Also provided in the appendix are the model parameters used in the Hodgkin and Huxley formulation of...
<p>Concentration responses of L, RS, LRS, and LRI to step changes in the ligand input rate. Two inpu...
Accurate ranking of efficacies and potencies of agonists is essential in the discovery of new select...
<p>Concentration-time profiles of ligand computed at medium cell density () for nM. These profiles ...
Many cellular reactions involve a reactant in solution binding to or dissociating from a reactant at...
<p>Ligand profiles computed as a function of distance at high cell density () and nM for s (A) and...
<p><b>A</b>) Species included in the mathematical model. The model consists of two distinct ligands,...
Short title: Algal receptor-like kinase for sexual reproduction Subject areas (primary): cell-cell i...
<p>The second scenario was applied, in which the total number of receptor A was fixed and the total ...
<p>(A). Dimerization curves. Black circles: Averaged dimeric fractions measured for the wild-type co...