In experiments where subjects are allocated to different treatments, implementing allocation concealment simply means that procedures are used to prevent conscious or unconscious human bias influencing the allocation of particular subjects to particular treatments. It is a related, but distinct, procedure to blinding. Allocation concealment is a neglected, but potentially valuable, tool in improving the design of experiments, and it can always be applied inexpensively and easily to any experiment involving allocation of subjects between treatment groups. I feel allocation concealment should be adopted more widely.Significance statementAllocation concealment simply means that the allocation of particular subjects to particular treatment grou...
Abstract Background If the randomisation process within a trial is subverted, this can lead to selec...
OBJECTIVE: To assess the association of the quality of allocation concealment with heterogeneity in ...
It is a matter of concern in many areas of investi-gation that systematic distortions can arise from...
In experiments where subjects are allocated to different treatments, implementing allocation conceal...
Assessing allocation concealment and blinding in randomised controlled trials: why bother? The scien...
Random assignment of individual participants in clinical trials entails two steps: (i) generating an...
Separating the act of randomisation from the person recruiting a trial participant is the keystone f...
Randomized controlled trials (RCT) are known as the best method to prove causality in spite of vario...
It is widely believed that baseline imbalances in randomized clinical trials must necessarily be ran...
“... having used a random allocation, the sternest critic is unable to say when we eventually dash i...
controlled trial of streptomycin for pulmonary tuberculosis should be regarded as a landmark is thus...
The rich history of blinding in clinical trials spans a couple of centuries.1 Most researchers world...
Acknowledgements The Health Services Research Unit is core funded by the Chief Scientist Office of t...
Objectives: To explore the theoretical justification for blinding in randomized trials and make reco...
BACKGROUND: Randomized trials without reported adequate allocation concealment have been shown to ov...
Abstract Background If the randomisation process within a trial is subverted, this can lead to selec...
OBJECTIVE: To assess the association of the quality of allocation concealment with heterogeneity in ...
It is a matter of concern in many areas of investi-gation that systematic distortions can arise from...
In experiments where subjects are allocated to different treatments, implementing allocation conceal...
Assessing allocation concealment and blinding in randomised controlled trials: why bother? The scien...
Random assignment of individual participants in clinical trials entails two steps: (i) generating an...
Separating the act of randomisation from the person recruiting a trial participant is the keystone f...
Randomized controlled trials (RCT) are known as the best method to prove causality in spite of vario...
It is widely believed that baseline imbalances in randomized clinical trials must necessarily be ran...
“... having used a random allocation, the sternest critic is unable to say when we eventually dash i...
controlled trial of streptomycin for pulmonary tuberculosis should be regarded as a landmark is thus...
The rich history of blinding in clinical trials spans a couple of centuries.1 Most researchers world...
Acknowledgements The Health Services Research Unit is core funded by the Chief Scientist Office of t...
Objectives: To explore the theoretical justification for blinding in randomized trials and make reco...
BACKGROUND: Randomized trials without reported adequate allocation concealment have been shown to ov...
Abstract Background If the randomisation process within a trial is subverted, this can lead to selec...
OBJECTIVE: To assess the association of the quality of allocation concealment with heterogeneity in ...
It is a matter of concern in many areas of investi-gation that systematic distortions can arise from...