BackgroundMeta-analyses of previous randomised controlled trials concluded that the smooth muscle relaxant drugs tamsulosin and nifedipine assisted stone passage for people managed expectantly for ureteric colic, but emphasised the need for high-quality trials with wide inclusion criteria. We aimed to fulfil this need by testing effectiveness of these drugs in a standard clinical care setting.MethodsFor this multicentre, randomised, placebo-controlled trial, we recruited adults (aged 18–65 years) undergoing expectant management for a single ureteric stone identified by CT at 24 UK hospitals. Participants were randomly assigned by a remote randomisation system to tamsulosin 400 μg, nifedipine 30 mg, or placebo taken daily for up to 4 weeks, ...
Study objectiveWe assess the efficacy and safety of tamsulosin compared with placebo as medical expu...
Study objective We assess the efficacy and safety of tamsulosin compared with placebo as medical exp...
Study objective We assess the efficacy and safety of tamsulosin compared with placebo as medical exp...
SummaryBackgroundMeta-analyses of previous randomised controlled trials concluded that the smooth mu...
RP, KS, KSt, GMa, RT, JB, GMc, AM, MK, KG, and SM report grants from National Institute for Health R...
SummaryBackgroundMeta-analyses of previous randomised controlled trials concluded that the smooth mu...
Background: Ureteric colic, the term used to describe the pain felt when a stone passes down the ure...
Background: Ureteric colic, the term used to describe the pain felt when a stone passes down the ure...
Acknowledgments Special thanks must go to all of the SUSPEND trial participants and staff at each of...
Urinary stone disease is common, with an estimated prevalence among the general population of 2% to ...
OBJECTIVE To determine the comparative efficacy of tamsulosin and nifedipine in medical expulsive...
This project was funded by the National Institute for Health Research Health Technology Assessment P...
Despite two decades of clinical use, the effectiveness of medical expulsive therapy (MET) for the no...
Introduction. Urolithiasis is one of the common disorder with which about 1/5th is found in the uret...
Funding This project was funded by the National Institute for Health Research Health Technology Asse...
Study objectiveWe assess the efficacy and safety of tamsulosin compared with placebo as medical expu...
Study objective We assess the efficacy and safety of tamsulosin compared with placebo as medical exp...
Study objective We assess the efficacy and safety of tamsulosin compared with placebo as medical exp...
SummaryBackgroundMeta-analyses of previous randomised controlled trials concluded that the smooth mu...
RP, KS, KSt, GMa, RT, JB, GMc, AM, MK, KG, and SM report grants from National Institute for Health R...
SummaryBackgroundMeta-analyses of previous randomised controlled trials concluded that the smooth mu...
Background: Ureteric colic, the term used to describe the pain felt when a stone passes down the ure...
Background: Ureteric colic, the term used to describe the pain felt when a stone passes down the ure...
Acknowledgments Special thanks must go to all of the SUSPEND trial participants and staff at each of...
Urinary stone disease is common, with an estimated prevalence among the general population of 2% to ...
OBJECTIVE To determine the comparative efficacy of tamsulosin and nifedipine in medical expulsive...
This project was funded by the National Institute for Health Research Health Technology Assessment P...
Despite two decades of clinical use, the effectiveness of medical expulsive therapy (MET) for the no...
Introduction. Urolithiasis is one of the common disorder with which about 1/5th is found in the uret...
Funding This project was funded by the National Institute for Health Research Health Technology Asse...
Study objectiveWe assess the efficacy and safety of tamsulosin compared with placebo as medical expu...
Study objective We assess the efficacy and safety of tamsulosin compared with placebo as medical exp...
Study objective We assess the efficacy and safety of tamsulosin compared with placebo as medical exp...