A stereospecific 7-step synthesis of (-)-indolactam V1 from tryptophan methyl ester is described. The key steps are the photocyclisation of the dichloroamide 6 to give the isomeric 7-hydroxy-7-isopropyl-pyrrolo[4,3,2-fg][3]benzazocines 16 + 18 and the nitrene-mediated ring expansion of the derived azide 5 to give the 9-membered imine 4. The synthesis is completed by stereoselective reduction of the imine bond and N-methylation.</p
The synthesis of 5,6-methylenedioxy-indol-3-yl-methanoic acid 8 and 5,6-methylenedioxy-indol-3-yl-ac...
The first section of this dissertation describes the synthesis of five indole-containing compounds u...
The stereoselective synthesis of a diverse set of functionalized indolizidine systems has been accom...
A stereospecific 7-step synthesis of (-)-indolactam V1 from tryptophan methyl ester is described. Th...
We report the total syntheses of (-)-indolactam V and the C7-substituted indolactam alkaloids (-)-pe...
The total synthesis of protein kinase C activator (-)-indolactam V (IL-V) has been successfully comp...
Cyclic imines 6a and 6b were obtained by the intramolecular 1,3-dipolar cycloaddition of azides with...
The total synthesis of a variety of indole and dihydroindole alkaloids, is described. Mere specifica...
The thermal decomposition of 2-azido-3-vinyl-1,4-quinones results in their smooth ring closure to in...
The synthetic efforts toward the concise synthesis of (−)-indolactam V from simple and commercially ...
A concise synthesis of the (-)-indolizidine alkaloid 167B and two formal syntheses of (-)-indolizidi...
The total synthesis of new indole alkaloids henrycinol A and B were accomplished starting from l-try...
This thesis describes synthetic approaches towards indolizidine and pyrrolidine alkaloids. The total...
The synthesis of 7-tryptamines was accomplished via the reduction of 7-nitrovinylindoles which were ...
BackgroundIndolizidine alkaloids widely occur in nature and display interesting biological activity....
The synthesis of 5,6-methylenedioxy-indol-3-yl-methanoic acid 8 and 5,6-methylenedioxy-indol-3-yl-ac...
The first section of this dissertation describes the synthesis of five indole-containing compounds u...
The stereoselective synthesis of a diverse set of functionalized indolizidine systems has been accom...
A stereospecific 7-step synthesis of (-)-indolactam V1 from tryptophan methyl ester is described. Th...
We report the total syntheses of (-)-indolactam V and the C7-substituted indolactam alkaloids (-)-pe...
The total synthesis of protein kinase C activator (-)-indolactam V (IL-V) has been successfully comp...
Cyclic imines 6a and 6b were obtained by the intramolecular 1,3-dipolar cycloaddition of azides with...
The total synthesis of a variety of indole and dihydroindole alkaloids, is described. Mere specifica...
The thermal decomposition of 2-azido-3-vinyl-1,4-quinones results in their smooth ring closure to in...
The synthetic efforts toward the concise synthesis of (−)-indolactam V from simple and commercially ...
A concise synthesis of the (-)-indolizidine alkaloid 167B and two formal syntheses of (-)-indolizidi...
The total synthesis of new indole alkaloids henrycinol A and B were accomplished starting from l-try...
This thesis describes synthetic approaches towards indolizidine and pyrrolidine alkaloids. The total...
The synthesis of 7-tryptamines was accomplished via the reduction of 7-nitrovinylindoles which were ...
BackgroundIndolizidine alkaloids widely occur in nature and display interesting biological activity....
The synthesis of 5,6-methylenedioxy-indol-3-yl-methanoic acid 8 and 5,6-methylenedioxy-indol-3-yl-ac...
The first section of this dissertation describes the synthesis of five indole-containing compounds u...
The stereoselective synthesis of a diverse set of functionalized indolizidine systems has been accom...