The early detection of changes to molecular pathways underlying Rheumatoid Arthritis (RA) is a key goal in Rheumatology. However, the standard disease scoring methods employed in the standard mouse model of RA, Collagen Induced Arthritis (CIA) cannot adequately quantify cellular or molecular processes. Here, we show that biofluorescence imaging can track in vivo processes contributing to disease and allow comparisons to be made of therapeutic drug efficacy earlier in disease progression
The Standard measures of experimental arthritis fail to detect, visualize, and quantify early inflam...
Objectives: RA is a chronic autoimmune disease leading to progressive destruction of cartilage and b...
ntroduction: Rheumatoid arthritis (RA) is an autoimmune disease leading to chronic synovial inflamma...
The early detection of changes to molecular pathways underlying Rheumatoid Arthritis (RA) is a key g...
The interaction of activated leukocytes with the rheumatoid synovial environment is a key process in...
AimTo quantify the progression and severity of mouse collagen-induced arthritis (CIA) using an in vi...
OBJECTIVE: In the present study we evaluated the use of four commercially available fluorescent prob...
In vivo molecular optical imaging has significant potential to delineate and measure, at the macrosc...
OBJECTIVE: In vivo optical imaging can delineate at the macroscopic level processes that are occurri...
BACKGROUND: Evolving immune-mediated therapeutic strategies for rheumatoid arthritis (RA) may benefi...
Item does not contain fulltextRheumatoid arthritis is an autoimmune disease resulting in chronic syn...
Background: Evolving immune-mediated therapeutic strategies for rheumatoid arthritis (RA) may benefi...
Anatomical imaging using radiological techniques have underpinned the investigation and monitoring o...
Rheumatoid arthritis (RA) affects millions of people world wide causing considerable human suffering...
In vivo mouse models of inflammatory arthritis are extensively used to investigate pathogenic mechan...
The Standard measures of experimental arthritis fail to detect, visualize, and quantify early inflam...
Objectives: RA is a chronic autoimmune disease leading to progressive destruction of cartilage and b...
ntroduction: Rheumatoid arthritis (RA) is an autoimmune disease leading to chronic synovial inflamma...
The early detection of changes to molecular pathways underlying Rheumatoid Arthritis (RA) is a key g...
The interaction of activated leukocytes with the rheumatoid synovial environment is a key process in...
AimTo quantify the progression and severity of mouse collagen-induced arthritis (CIA) using an in vi...
OBJECTIVE: In the present study we evaluated the use of four commercially available fluorescent prob...
In vivo molecular optical imaging has significant potential to delineate and measure, at the macrosc...
OBJECTIVE: In vivo optical imaging can delineate at the macroscopic level processes that are occurri...
BACKGROUND: Evolving immune-mediated therapeutic strategies for rheumatoid arthritis (RA) may benefi...
Item does not contain fulltextRheumatoid arthritis is an autoimmune disease resulting in chronic syn...
Background: Evolving immune-mediated therapeutic strategies for rheumatoid arthritis (RA) may benefi...
Anatomical imaging using radiological techniques have underpinned the investigation and monitoring o...
Rheumatoid arthritis (RA) affects millions of people world wide causing considerable human suffering...
In vivo mouse models of inflammatory arthritis are extensively used to investigate pathogenic mechan...
The Standard measures of experimental arthritis fail to detect, visualize, and quantify early inflam...
Objectives: RA is a chronic autoimmune disease leading to progressive destruction of cartilage and b...
ntroduction: Rheumatoid arthritis (RA) is an autoimmune disease leading to chronic synovial inflamma...