Double asymmetric induction has been employed as a tool to optimise pyrazolidinone-derived organo-catalysts for the asymmetric iminium ion catalysed Diels-Alder reaction. Mechanistic studies revealed a superior hydrazide catalyst deriving from methanolysis of the chiral pyrazolidinone precursor. This catalyst displays unusually high endo diastereoselectivity and good enantioselectivity with a range of beta-arylenals and cyclic dienes at catalyst loadings as low as 1 mol%.</p
The organocatalytic amination of pyrazol-5-ones with azodicarboxylates (catalyzed by quinine) is rep...
This thesis embraces two main sections that examine alternative architectures for the iminium ion ca...
α,β‐unsaturated aldehydes have been traditionally used in LUMO lowering asymmetric aminocatalysis (i...
Novel cyclic hydrazides were designed and found to function as asymmetric organocatalysts in aqueous...
This thesis principally focuses on the development of a novel series of asymmetric iminium ion organ...
A range of pyrazolidin-3-ones have been prepared and their activity as catalysts for iminium-ion pro...
Our laboratory has been engaged in the design of broadly useful new strategies for enantioselective ...
Our laboratory has been engaged in the design of broadly useful new strategies for enantioselective ...
The development of novel, high-yielding, and selective methodologies for the asymmetric synthesis of...
Density functional theory calculations (M06-2X//B3LYP) have been performed to determine the factors ...
This poster will describe a novel series of mol. scaffolds for the acceleration of iminium ion catal...
An asymmetric Diels–Alder reaction of 2-methyl-3-indolylmethanols and α,β-unsaturated aldehydes has ...
396 : il., graf.In the work compiled in this thesis is presented a series of strategies that have be...
The first organocatalytic highly enantioselective reactions of substituted alpha-cyanoacetates and b...
Enantioselective organocatalytic asymmetric Diels-Alder reactions provide a facile and efficient ro...
The organocatalytic amination of pyrazol-5-ones with azodicarboxylates (catalyzed by quinine) is rep...
This thesis embraces two main sections that examine alternative architectures for the iminium ion ca...
α,β‐unsaturated aldehydes have been traditionally used in LUMO lowering asymmetric aminocatalysis (i...
Novel cyclic hydrazides were designed and found to function as asymmetric organocatalysts in aqueous...
This thesis principally focuses on the development of a novel series of asymmetric iminium ion organ...
A range of pyrazolidin-3-ones have been prepared and their activity as catalysts for iminium-ion pro...
Our laboratory has been engaged in the design of broadly useful new strategies for enantioselective ...
Our laboratory has been engaged in the design of broadly useful new strategies for enantioselective ...
The development of novel, high-yielding, and selective methodologies for the asymmetric synthesis of...
Density functional theory calculations (M06-2X//B3LYP) have been performed to determine the factors ...
This poster will describe a novel series of mol. scaffolds for the acceleration of iminium ion catal...
An asymmetric Diels–Alder reaction of 2-methyl-3-indolylmethanols and α,β-unsaturated aldehydes has ...
396 : il., graf.In the work compiled in this thesis is presented a series of strategies that have be...
The first organocatalytic highly enantioselective reactions of substituted alpha-cyanoacetates and b...
Enantioselective organocatalytic asymmetric Diels-Alder reactions provide a facile and efficient ro...
The organocatalytic amination of pyrazol-5-ones with azodicarboxylates (catalyzed by quinine) is rep...
This thesis embraces two main sections that examine alternative architectures for the iminium ion ca...
α,β‐unsaturated aldehydes have been traditionally used in LUMO lowering asymmetric aminocatalysis (i...