A highly diastereoselective synthesis of chiral ring-fused isoindolinone products, the skeleton of which is common to many naturally occurring and biologically active compounds, is achieved in only two synthetic steps from readily available precursors via an N-acyliminium ion cyclization reaction of an isoindolinone substrate. (C) 1998 Elsevier Science Ltd. All rights reserved.</p
New methodology for the synthesis of non-racemic isoindolinone targets has been developed through ap...
A highly stereoselective access to 3-sulfinyl-substituted isoindolinones has been achieved by a tand...
A new method for the direct, stereoselective synthesis of highly functionalized 1,3-disubstituted is...
A highly diastereoselective synthesis of chiral ring-fused isoindolinone products, the skeleton of w...
Addition of in situ generated di- or trisubstituted alkenylalanes to N-acyliminium ions provides rap...
A simple methodology has been developed for the synthesis of substituted pyrroloisoindolone and pyri...
A highly diastereoselective method for the synthesis of 3-substituted isoindolin-1-ones has been dev...
A highly diastereoselective method for the synthesis of 3-substituted isoindolin-1-ones has been dev...
A new, versatile and highly stereoselective approach for the synthesis of non-racemic 3-substituted ...
Condensation of 2-formylbenzoic acid with alpha-amino alcohol substrates proceeds with extremely hig...
A new approach for the synthesis of non-racemic 3-substituted isoindolin-1-one targets has been deve...
The mechanism of a base-catalyzed one-pot reaction of 2-cyanobenzaldehyde and primary nitroalkanes, ...
A stereoselective <i>N</i>-iminium ion cyclization with allylsilane to construct vicinal quaternary–...
International audienceIsoindolo[2,1-a]quinolines 10, 11, 12 were synthesized from hydroxylactams 8 o...
In a reaction catalyzed by a chiral phosphoric acid, ketones and in situ generated ketimines afford ...
New methodology for the synthesis of non-racemic isoindolinone targets has been developed through ap...
A highly stereoselective access to 3-sulfinyl-substituted isoindolinones has been achieved by a tand...
A new method for the direct, stereoselective synthesis of highly functionalized 1,3-disubstituted is...
A highly diastereoselective synthesis of chiral ring-fused isoindolinone products, the skeleton of w...
Addition of in situ generated di- or trisubstituted alkenylalanes to N-acyliminium ions provides rap...
A simple methodology has been developed for the synthesis of substituted pyrroloisoindolone and pyri...
A highly diastereoselective method for the synthesis of 3-substituted isoindolin-1-ones has been dev...
A highly diastereoselective method for the synthesis of 3-substituted isoindolin-1-ones has been dev...
A new, versatile and highly stereoselective approach for the synthesis of non-racemic 3-substituted ...
Condensation of 2-formylbenzoic acid with alpha-amino alcohol substrates proceeds with extremely hig...
A new approach for the synthesis of non-racemic 3-substituted isoindolin-1-one targets has been deve...
The mechanism of a base-catalyzed one-pot reaction of 2-cyanobenzaldehyde and primary nitroalkanes, ...
A stereoselective <i>N</i>-iminium ion cyclization with allylsilane to construct vicinal quaternary–...
International audienceIsoindolo[2,1-a]quinolines 10, 11, 12 were synthesized from hydroxylactams 8 o...
In a reaction catalyzed by a chiral phosphoric acid, ketones and in situ generated ketimines afford ...
New methodology for the synthesis of non-racemic isoindolinone targets has been developed through ap...
A highly stereoselective access to 3-sulfinyl-substituted isoindolinones has been achieved by a tand...
A new method for the direct, stereoselective synthesis of highly functionalized 1,3-disubstituted is...