Antimycobacterial drugs are used in the treatment of diseases caused by members of the Mycobacterium genus, including tuberculosis(TB) and leprosy, which have affected man since antiquity, and the non-tuberculous mycobacterioses (NTM) that are increasingly recognised. Combination chemotherapy is essential to kill heterogenuous populations of bacterial cells located in different conditions within the host, and to prevent drug resistance. Whilst combination therapy has been effective in controlling leprosy, the global HIV epidemic and the emergence drug resistance are undermining efforts to control tuberculosis. Currently available chemotherapeutic agents are highly effective in managing drug sensitive tuberculosis, however, the development o...
The inappropriate treatment of drug-susceptible tuberculosis can lead to the selection and trans-mis...
Mycobacteriosis is mainly caused by two groups of species: Mycobacterium tuberculosis and non-tuberc...
Despite the development of effective treatments, tuberculosis (TB) remains a major health problem. T...
Antimicrobial resistance, the so-called silent pandemic, is pushing industry and academia to find no...
Tuberculosis (TB) remains the major health problem causing morbidity and mortality throughout the wo...
Mycobacterial infections are among the most widespread infectious diseases worldwide. For instance, ...
At. present, clinical management of patients infected with Mycobacterium tuberculosis faces difficul...
The emergence and spread of M. tuberculosis multidrug-resistant (MDR-TB), extensively drug-resistant...
Tuberculosis has for decades been the leading cause of death, worldwide, originating from merely one...
The nontuberculous mycobacteria (NTM), defined as any mycobacterial pathogen other than Mycobacteriu...
One important agenda in the sustainable development goals is the eradication of infectious diseases ...
For the first time in 40 years, a portfolio of promising new compounds for the treatment of tubercul...
Tuberculosis (TB) is caused by a bacterium called Mycobacterium tuberculosis usually attack the lung...
International audienceDespite the low expensive and effective four-drug treatment regimen (isoniazid...
Tuberculosis is a contagious disease with high mortality worldwide. The recent emergence of cases of...
The inappropriate treatment of drug-susceptible tuberculosis can lead to the selection and trans-mis...
Mycobacteriosis is mainly caused by two groups of species: Mycobacterium tuberculosis and non-tuberc...
Despite the development of effective treatments, tuberculosis (TB) remains a major health problem. T...
Antimicrobial resistance, the so-called silent pandemic, is pushing industry and academia to find no...
Tuberculosis (TB) remains the major health problem causing morbidity and mortality throughout the wo...
Mycobacterial infections are among the most widespread infectious diseases worldwide. For instance, ...
At. present, clinical management of patients infected with Mycobacterium tuberculosis faces difficul...
The emergence and spread of M. tuberculosis multidrug-resistant (MDR-TB), extensively drug-resistant...
Tuberculosis has for decades been the leading cause of death, worldwide, originating from merely one...
The nontuberculous mycobacteria (NTM), defined as any mycobacterial pathogen other than Mycobacteriu...
One important agenda in the sustainable development goals is the eradication of infectious diseases ...
For the first time in 40 years, a portfolio of promising new compounds for the treatment of tubercul...
Tuberculosis (TB) is caused by a bacterium called Mycobacterium tuberculosis usually attack the lung...
International audienceDespite the low expensive and effective four-drug treatment regimen (isoniazid...
Tuberculosis is a contagious disease with high mortality worldwide. The recent emergence of cases of...
The inappropriate treatment of drug-susceptible tuberculosis can lead to the selection and trans-mis...
Mycobacteriosis is mainly caused by two groups of species: Mycobacterium tuberculosis and non-tuberc...
Despite the development of effective treatments, tuberculosis (TB) remains a major health problem. T...