Add to ORKGRecent findings from comparative and evolutionary physiologists reveal novel insights into the regulation of inflammation and immune function under conditions of chronic-sustained and intermittent hypoxia. Comparative approaches provide a valuable gateway for discovering essential principals of physiology and adaptive molecular strategies utilized in nature that protect against clinically relevant stressors, which can guide therapeutic developments in biomedical science
Oxygen is a molecule that is central to cellular respiration and viability, yet there are multiple p...
The hypoxic response in cells and tissues is mediated by the family of hypoxia-inducible factor (HIF...
Hypoxia and bacterial infection frequently co-exist, in both acute and chronic clinical settings, an...
Hypoxia is a hallmark of inflamed, infected or damaged tissue, and the adaptation to inadequate tiss...
The syndrome of critical illness is a complex physiological stressor that can be triggered by divers...
Contains fulltext : 172742.pdf (publisher's version ) (Closed access)Hypoxia and i...
Oxygen availability varies throughout the human body in health and disease. Under physiological cond...
The correct concentration of oxygen in all tissues is a hallmark of cellular wellness, and the negat...
Introduction: Organisms are exposed to oxygen deprivation (Hypoxia) in various physiological and pat...
Oxygen homeostasis reflects the constant body requirement to generate energy. Hypoxia (0.1–1% O2), p...
Uncontrolled inflammation underpins a diverse range of diseases where effective therapy remains an u...
Innate immunity is the first line of defence against invading pathogens and is also required for the...
When tissues are insufficiently supplied with oxygen, the environment is said to be hypoxic. Acute (...
Hypoxia can have profound effects on individual organisms. This chapter focuses on the mechanisms di...
With little in the way of effective therapeutic strategies to target the innate immune response, a b...
Oxygen is a molecule that is central to cellular respiration and viability, yet there are multiple p...
The hypoxic response in cells and tissues is mediated by the family of hypoxia-inducible factor (HIF...
Hypoxia and bacterial infection frequently co-exist, in both acute and chronic clinical settings, an...
Hypoxia is a hallmark of inflamed, infected or damaged tissue, and the adaptation to inadequate tiss...
The syndrome of critical illness is a complex physiological stressor that can be triggered by divers...
Contains fulltext : 172742.pdf (publisher's version ) (Closed access)Hypoxia and i...
Oxygen availability varies throughout the human body in health and disease. Under physiological cond...
The correct concentration of oxygen in all tissues is a hallmark of cellular wellness, and the negat...
Introduction: Organisms are exposed to oxygen deprivation (Hypoxia) in various physiological and pat...
Oxygen homeostasis reflects the constant body requirement to generate energy. Hypoxia (0.1–1% O2), p...
Uncontrolled inflammation underpins a diverse range of diseases where effective therapy remains an u...
Innate immunity is the first line of defence against invading pathogens and is also required for the...
When tissues are insufficiently supplied with oxygen, the environment is said to be hypoxic. Acute (...
Hypoxia can have profound effects on individual organisms. This chapter focuses on the mechanisms di...
With little in the way of effective therapeutic strategies to target the innate immune response, a b...
Oxygen is a molecule that is central to cellular respiration and viability, yet there are multiple p...
The hypoxic response in cells and tissues is mediated by the family of hypoxia-inducible factor (HIF...
Hypoxia and bacterial infection frequently co-exist, in both acute and chronic clinical settings, an...