Predicted structures of eukaryotic histone homodimer.
- Haiqing Zhao (2937306)
- Hao Wu (65943)
- Alex Guseman (17743429)
- Dulith Abeykoon (4916302)
- Christina M. Camara (17743432)
- Yamini Dalal (33140)
- David Fushman (239364)
- Garegin A. Papoian (691984)
Publication date
January 2024
DOIAbstract
(A) AWSEM and AlphaFold2 predicted homodimer structures of H2A/H2A align well with the native heterodimer structure of H2A/H2B (colored in blue, orange, and green). (B) RMSF analysis of all-atom simulations demonstrates comparable stabilities of AWSEM- and AlphaFold2-predicted homo-complex structures (in blue and orange). RMSF of two chains are plotted separately and helix regions are animated by cartoon in grey.</p
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