Abstract Background Hepatic insulin clearance (HIC) is an important pathophysiology of type 2 diabetes mellitus (T2DM). HIC was reported to decrease in patients with type 2 diabetes and metabolic syndrome. HIC is originally calculated by post-load insulin and C-peptide from the oral glucose tolerance test (OGTT). However, OGTT or meal tolerance tests are a burden for patients, and OGTT is not suitable for overt diabetes due to the risk of hyperglycemia. If we can calculate the HIC from the fasting state, it is preferable. We hypothesized that fasting HIC correlates with postprandial HIC in both participants with T2DM and without diabetes. We investigated whether fasting HIC correlates with postprandial HIC in overt T2DM and nondiabetes subj...
Introduction Fasting metabolite profiles have been shown to distinguish type 2 diabetes (T2D) patien...
OBJECTIVE — In this study, we sought to determine whether postprandial insulin secretion, insulin ac...
Several methods have been used for diagnosing insulin resistance in humans. Glycemic clamp continues...
Introduction Hepatic insulin clearance (HIC) is an important pathophysiology of type 2 diabetes. HIC...
Reduced insulin clearance has been shown to predict the development of type 2 diabetes. Recently, it...
Reduced insulin clearance has been shown to predict the development of type 2 diabetes. Recently, it...
BACKGROUND:Increased hepatic insulin clearance (HIC) is important in the pathophysiology of type 2 d...
OBJECTIVE: Type-2 diabetes is a progressive disease. However, little is known about whether decrease...
Thirty-two subjects with impaired fasting glucose (IFG) and 28 subjects with normal fasting glucose ...
OBJECTIVE — To compare the pathophysiology of impaired fasting glucose (IFG) and im-paired glucose t...
The relative impact of hepatic glucose production (HGP) and peripheral glucose uptake (GU) on plasma...
Introduction: Fasting metabolite profiles have been shown to distinguish type 2 diabetes (T2D) patie...
Context: Subjects with normal glucose tolerance (NGT) but 1-h postload glucose = 155 mg/dL (NGT-1h-h...
Hyperproinsulinemia is an indicator of β-cell dysfunction, and fasting proinsulin levels are elevate...
Aims/hypothesis\u2002 Individuals with impaired fasting glucose (IFG) are at increased risk of devel...
Introduction Fasting metabolite profiles have been shown to distinguish type 2 diabetes (T2D) patien...
OBJECTIVE — In this study, we sought to determine whether postprandial insulin secretion, insulin ac...
Several methods have been used for diagnosing insulin resistance in humans. Glycemic clamp continues...
Introduction Hepatic insulin clearance (HIC) is an important pathophysiology of type 2 diabetes. HIC...
Reduced insulin clearance has been shown to predict the development of type 2 diabetes. Recently, it...
Reduced insulin clearance has been shown to predict the development of type 2 diabetes. Recently, it...
BACKGROUND:Increased hepatic insulin clearance (HIC) is important in the pathophysiology of type 2 d...
OBJECTIVE: Type-2 diabetes is a progressive disease. However, little is known about whether decrease...
Thirty-two subjects with impaired fasting glucose (IFG) and 28 subjects with normal fasting glucose ...
OBJECTIVE — To compare the pathophysiology of impaired fasting glucose (IFG) and im-paired glucose t...
The relative impact of hepatic glucose production (HGP) and peripheral glucose uptake (GU) on plasma...
Introduction: Fasting metabolite profiles have been shown to distinguish type 2 diabetes (T2D) patie...
Context: Subjects with normal glucose tolerance (NGT) but 1-h postload glucose = 155 mg/dL (NGT-1h-h...
Hyperproinsulinemia is an indicator of β-cell dysfunction, and fasting proinsulin levels are elevate...
Aims/hypothesis\u2002 Individuals with impaired fasting glucose (IFG) are at increased risk of devel...
Introduction Fasting metabolite profiles have been shown to distinguish type 2 diabetes (T2D) patien...
OBJECTIVE — In this study, we sought to determine whether postprandial insulin secretion, insulin ac...
Several methods have been used for diagnosing insulin resistance in humans. Glycemic clamp continues...