The gut microbiota and microbial metabolites influence the enteric nervous system and the central nervous system via the microbial–gut–brain axis. Increasing body of evidence suggests that disturbances in the metabolism of peripheral branched-chain amino acids (BCAAs) can contribute to the development of neurodegenerative diseases through neuroinflammatory signaling. Preliminary research has shown that longitudinal changes in serum amino acid levels in mouse models of Parkinson’s disease (PD) are negatively correlated with disease progression. Therefore, the aim of the present study was to determine the changes in serum levels of short-chain fatty acids (SCFAs) in a mouse model of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced ...
peer reviewedParkinson’s disease (PD) exhibits systemic effects on human metabolism with emerging ro...
Abstract Background Untargeted high-resolution metabolomic profiling provides simultaneous measureme...
Parkinson's disease (PD) exhibits systemic effects on the human metabolism, with emerging roles for ...
Introduction: Parkinson’s disease (PD) is the second most common neurodegenerative disorder, w...
For people with Parkinson’s disease (PD), considered the most common neurodegenerative disease behin...
Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cas...
We aimed to investigate the link between serum metabolites, gut bacterial community composition, and...
Biomarker research in Parkinson’s disease (PD) has long been dominated by measuring dopamine metabol...
Parkinson's disease is a neurodegenerative disorder characterized by the accumulation of intracellul...
Metabolic confusion has been linked to the pathogenesis of Parkinson's disease (PD), while the dynam...
The aggregation of alpha-synuclein protein (αSyn) is a hallmark of Parkinson’s disease (PD). Conside...
Parkinson ’ s disease (PD) is a multifactorial neurodegenerative disorder in which environmental (li...
The research of new biomarkers for Parkinson's disease is essential for accurate and precocious diag...
Mucopolysaccharidoses (MPSs) are inherited disorders of the glycosaminoglycan (GAG) metabolism. The...
Background: Accumulation of the α-synuclein (α-syn) protein and depletion of dopaminergic neurons in...
peer reviewedParkinson’s disease (PD) exhibits systemic effects on human metabolism with emerging ro...
Abstract Background Untargeted high-resolution metabolomic profiling provides simultaneous measureme...
Parkinson's disease (PD) exhibits systemic effects on the human metabolism, with emerging roles for ...
Introduction: Parkinson’s disease (PD) is the second most common neurodegenerative disorder, w...
For people with Parkinson’s disease (PD), considered the most common neurodegenerative disease behin...
Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cas...
We aimed to investigate the link between serum metabolites, gut bacterial community composition, and...
Biomarker research in Parkinson’s disease (PD) has long been dominated by measuring dopamine metabol...
Parkinson's disease is a neurodegenerative disorder characterized by the accumulation of intracellul...
Metabolic confusion has been linked to the pathogenesis of Parkinson's disease (PD), while the dynam...
The aggregation of alpha-synuclein protein (αSyn) is a hallmark of Parkinson’s disease (PD). Conside...
Parkinson ’ s disease (PD) is a multifactorial neurodegenerative disorder in which environmental (li...
The research of new biomarkers for Parkinson's disease is essential for accurate and precocious diag...
Mucopolysaccharidoses (MPSs) are inherited disorders of the glycosaminoglycan (GAG) metabolism. The...
Background: Accumulation of the α-synuclein (α-syn) protein and depletion of dopaminergic neurons in...
peer reviewedParkinson’s disease (PD) exhibits systemic effects on human metabolism with emerging ro...
Abstract Background Untargeted high-resolution metabolomic profiling provides simultaneous measureme...
Parkinson's disease (PD) exhibits systemic effects on the human metabolism, with emerging roles for ...