Add to ORKGMendelian randomisation and polygenic risk score analysis have become increasingly popular in the last decade due to the advent of large-scale genome-wide association studies. Each approach has valuable applications, some of which are overlapping, yet there are important differences which we describe here
Polygenic risk scores (PRSs) have been widely explored in precision medicine. However, few studies h...
Mendelian randomization uses genetic variants to make causal inferences about the effect of a risk f...
Polygenic risk scores (PRS) from genome-wide association studies (GWAS) are increasingly used to pre...
Mendelian randomization (MR) is a technique that seeks to establish causation between an exposure an...
Many exposures considered in Mendelian randomization (MR) studies are polygenic in that they are inf...
Polygenic risk scores (PRS) are proposed for use in clinical and research settings for risk stratifi...
An observational correlation between a suspected risk factor and an outcome does not necessarily imp...
Mendelian randomization (MR) studies typically assess the pathogenic relevance of environmental expo...
Genome-wide association studies have shown unequivocally that common complex disorders have a polyge...
The number of Mendelian randomization (MR) analyses including large numbers of genetic variants is r...
This paper explores the interpretation and use of polygenic risk scores (PRSs). We argue that PRSs g...
Abstract The prediction of disease risks is an essential part of personalized medicine, which includ...
Background Polygenic risk scores (PRS) have been widely applied in research studies, showing how pop...
Here, we argue that polygenic risk scores (PRSs) are different epistemic objects as compared to othe...
Mendelian randomization (MR) studies typically assess the pathogenic relevance of environmental expo...
Polygenic risk scores (PRSs) have been widely explored in precision medicine. However, few studies h...
Mendelian randomization uses genetic variants to make causal inferences about the effect of a risk f...
Polygenic risk scores (PRS) from genome-wide association studies (GWAS) are increasingly used to pre...
Mendelian randomization (MR) is a technique that seeks to establish causation between an exposure an...
Many exposures considered in Mendelian randomization (MR) studies are polygenic in that they are inf...
Polygenic risk scores (PRS) are proposed for use in clinical and research settings for risk stratifi...
An observational correlation between a suspected risk factor and an outcome does not necessarily imp...
Mendelian randomization (MR) studies typically assess the pathogenic relevance of environmental expo...
Genome-wide association studies have shown unequivocally that common complex disorders have a polyge...
The number of Mendelian randomization (MR) analyses including large numbers of genetic variants is r...
This paper explores the interpretation and use of polygenic risk scores (PRSs). We argue that PRSs g...
Abstract The prediction of disease risks is an essential part of personalized medicine, which includ...
Background Polygenic risk scores (PRS) have been widely applied in research studies, showing how pop...
Here, we argue that polygenic risk scores (PRSs) are different epistemic objects as compared to othe...
Mendelian randomization (MR) studies typically assess the pathogenic relevance of environmental expo...
Polygenic risk scores (PRSs) have been widely explored in precision medicine. However, few studies h...
Mendelian randomization uses genetic variants to make causal inferences about the effect of a risk f...
Polygenic risk scores (PRS) from genome-wide association studies (GWAS) are increasingly used to pre...