Mechanistic target of rapamycin complex (mTORC)1 is the major regulator of metabolism at the cellular and organismal level. mTORC1-mediated regulatory feedback loops enable adaptation to nutrient and growth factor availability and metabolic demand. In their recent study, Yoneyama et al. have identified and characterized a negative feedback loop from mTORC1 to insulin receptor substrate (IRS)1; the key component of the insulin/insulin-like growth factor (IGF) signaling pathway
mTOR (mammalian target of rapamycin) is a highly conserved serine/threonine protein kinase that has ...
The mechanistic target of rapamycin (mTOR) kinase is a conserved regulator of cell growth, prolifera...
The insulin receptor substrate-1 (IRS1) is phosphorylated on serine 307 (human sequence, correspondi...
The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that controls a wide spectrum ...
Summary: The insulin receptor substrate IRS-1 is a key substrate of insulin and insulin-like growth ...
The mammalian target of rapamycin (mTOR) is a protein kinase that plays key roles in cellular regula...
Mammalian target of rapamycin complex I (mTORC1) is an atypical Ser/Thr kinase that regulates cellul...
<p>Insulin Receptor substrate 1 (IRS1) and Phosphatidylinositol 3-kinases (PI3K) are activated by In...
Dysregulated mitochondrial metabolism during hepatic insulin resistance may contribute to pathophysi...
The kinase mammalian target of rapamycin (mTOR) exists in two multiprotein complexes (mTORC1 and mTO...
Mammalian target of rapamycin (mTOR) kinase responds to growth factors, nutrients and cellular energ...
ABSTRACT The mechanistic target of rapamycin (mTOR) signaling pathway regulates many metabolic and p...
The mammalian target of rapamycin (mTOR) signalling pathway is implicated in the pathogenesis of a n...
The mammalian target of rapamycin (mTOR) is an evolutionally conserved protein kinase and a central ...
OBJECTIVE—The purpose of this study was to evaluate the role of the S6K arm of mammalian target of r...
mTOR (mammalian target of rapamycin) is a highly conserved serine/threonine protein kinase that has ...
The mechanistic target of rapamycin (mTOR) kinase is a conserved regulator of cell growth, prolifera...
The insulin receptor substrate-1 (IRS1) is phosphorylated on serine 307 (human sequence, correspondi...
The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that controls a wide spectrum ...
Summary: The insulin receptor substrate IRS-1 is a key substrate of insulin and insulin-like growth ...
The mammalian target of rapamycin (mTOR) is a protein kinase that plays key roles in cellular regula...
Mammalian target of rapamycin complex I (mTORC1) is an atypical Ser/Thr kinase that regulates cellul...
<p>Insulin Receptor substrate 1 (IRS1) and Phosphatidylinositol 3-kinases (PI3K) are activated by In...
Dysregulated mitochondrial metabolism during hepatic insulin resistance may contribute to pathophysi...
The kinase mammalian target of rapamycin (mTOR) exists in two multiprotein complexes (mTORC1 and mTO...
Mammalian target of rapamycin (mTOR) kinase responds to growth factors, nutrients and cellular energ...
ABSTRACT The mechanistic target of rapamycin (mTOR) signaling pathway regulates many metabolic and p...
The mammalian target of rapamycin (mTOR) signalling pathway is implicated in the pathogenesis of a n...
The mammalian target of rapamycin (mTOR) is an evolutionally conserved protein kinase and a central ...
OBJECTIVE—The purpose of this study was to evaluate the role of the S6K arm of mammalian target of r...
mTOR (mammalian target of rapamycin) is a highly conserved serine/threonine protein kinase that has ...
The mechanistic target of rapamycin (mTOR) kinase is a conserved regulator of cell growth, prolifera...
The insulin receptor substrate-1 (IRS1) is phosphorylated on serine 307 (human sequence, correspondi...
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