A-C. Plots of eggs per gram of feces (EPG) by days post infection of WT mice infected with STAT6 KO- or WT-adapted N. brasiliensis percentage of surviving adults from the initial inoculum number shown below. Number of generations of adaptation and sex of mice noted as generations in STAT6 KO/WT mice above plots. Data collected until day 9 (A), day 8 (B), or day 7 (C) post infection. (TIF)</p
Dobson C., Sitepu P. and Brindley P. J. 1985. Influence of primary infection on the population dynam...
<p>Gametocyte (transmission stage) dynamics (top four rows) of individual mice in mixed infections o...
<p>Mice were killed at week 21 (A) and week 43 (B) after infection. Asterisks show strains that exhi...
STAT6 KO-adapted N. brasiliensis do not exhibit attenuation of fitness when challenged within WT mic...
A. Survival curve with average host survival by days post infection for WT hosts infected with WT-ad...
A. Average eggs per gram of feces by days post infection, with SEM error bars. B. Average area under...
Summary of regression analysis of host immune cell populations versus hookworm adaptation genotypes,...
A. Experimental evolution design, N. brasiliensis (originally isolated from rat host, brown) were in...
A. Experimental design. B. Number of parasites in the lungs after 24 hours, 48 hours, or 5 days post...
Mesenteric lymph node data (A-J) A. Experimental design; Parental worms infected WT or STAT6 KO mice...
Complete GSEA results in G15/14 adapted day 7 adult worms from WT or STAT6 KO mice.</p
Supernatant from 3-day cultures of WT or STAT6 KO- adapted (G24/23) N. brasiliensis was used to stim...
STAT6 KO-adapted N. brasiliensis elicit a stronger inflammatory WT host immune response. Mesenteric ...
Graphical summary. WT-adapted hookworms within WT host environment (upper left box) have impeded sur...
N. brasiliensis has an altered transcriptional profile within STAT6 KO hosts. A. Experimental design...
Dobson C., Sitepu P. and Brindley P. J. 1985. Influence of primary infection on the population dynam...
<p>Gametocyte (transmission stage) dynamics (top four rows) of individual mice in mixed infections o...
<p>Mice were killed at week 21 (A) and week 43 (B) after infection. Asterisks show strains that exhi...
STAT6 KO-adapted N. brasiliensis do not exhibit attenuation of fitness when challenged within WT mic...
A. Survival curve with average host survival by days post infection for WT hosts infected with WT-ad...
A. Average eggs per gram of feces by days post infection, with SEM error bars. B. Average area under...
Summary of regression analysis of host immune cell populations versus hookworm adaptation genotypes,...
A. Experimental evolution design, N. brasiliensis (originally isolated from rat host, brown) were in...
A. Experimental design. B. Number of parasites in the lungs after 24 hours, 48 hours, or 5 days post...
Mesenteric lymph node data (A-J) A. Experimental design; Parental worms infected WT or STAT6 KO mice...
Complete GSEA results in G15/14 adapted day 7 adult worms from WT or STAT6 KO mice.</p
Supernatant from 3-day cultures of WT or STAT6 KO- adapted (G24/23) N. brasiliensis was used to stim...
STAT6 KO-adapted N. brasiliensis elicit a stronger inflammatory WT host immune response. Mesenteric ...
Graphical summary. WT-adapted hookworms within WT host environment (upper left box) have impeded sur...
N. brasiliensis has an altered transcriptional profile within STAT6 KO hosts. A. Experimental design...
Dobson C., Sitepu P. and Brindley P. J. 1985. Influence of primary infection on the population dynam...
<p>Gametocyte (transmission stage) dynamics (top four rows) of individual mice in mixed infections o...
<p>Mice were killed at week 21 (A) and week 43 (B) after infection. Asterisks show strains that exhi...