Antibiotic resistance in Enterococcus faecium, Enterococcus faecalis, and Staphylococcus aureus remains a major public health concern worldwide. Furthermore, these microbes frequently co-exist in biofilm-associated infections, largely nullifying antibiotic-based therapy. Therefore, it is imperative to develop an efficient therapeutic strategy for combating infections caused by polymicrobial biofilms. In this study, we investigated the antibacterial and antibiofilm activity of the bacteriophage endolysin Ply113 in vitro. Ply113 exhibited high and rapid lytic activity against E. faecium, E. faecalis, and S. aureus, including vancomycin-resistant Enterococcus and methicillin-resistant S. aureus isolates. Transmission electron microscopy reveal...
<p>Shiga toxin (Stx) producing E. coli (STEC) such as Enterohemorrhagic E. coli (EHEC) are the major...
Peptidoglycan lytic enzymes (endolysins) induce bacterial host cell lysis in the late phase of the l...
The formation of a Pseudomonas aeruginosa biofilm, a complex structure enclosing bacterial cells in ...
Antibiotic resistance in Enterococcus faecium, Enterococcus faecalis, and Staphylococcus aureus rema...
Biofilms are the most common lifestyle of bacteria in both natural and human environments. The orga...
<p>Biofilm infection is now understood to be a potent contributor to the recalcitrant nature of chro...
Enterococcus faecalis is a Gram-positive opportunistic pathogen that could cause pneumonia and bacte...
Antibiotic misuse and overuse has prompted bacteria to rapidly develop resistance, thereby hindering...
Bacterial vaginosis (BV) is the most frequent vaginal infection in women of reproductive age. It is ...
Biofilm formation is a common strategy utilized by bacterial pathogens to establish persistence in a...
AbstractBacteria in most environments encase themselves in a hydrated matrix of polysaccharide and p...
With widespread abuse of antibiotics, bacterial resistance has increasingly become a serious threat....
Staphylococcus aureus is one of the most relevant opportunistic pathogens involved in many biofilm-a...
tissues and form biofilms. Significantly, these biofilms are a contributing mechanism of antibiotic ...
<div><p>Staphylococcal biofilms are a major concern in both clinical and food settings because they ...
<p>Shiga toxin (Stx) producing E. coli (STEC) such as Enterohemorrhagic E. coli (EHEC) are the major...
Peptidoglycan lytic enzymes (endolysins) induce bacterial host cell lysis in the late phase of the l...
The formation of a Pseudomonas aeruginosa biofilm, a complex structure enclosing bacterial cells in ...
Antibiotic resistance in Enterococcus faecium, Enterococcus faecalis, and Staphylococcus aureus rema...
Biofilms are the most common lifestyle of bacteria in both natural and human environments. The orga...
<p>Biofilm infection is now understood to be a potent contributor to the recalcitrant nature of chro...
Enterococcus faecalis is a Gram-positive opportunistic pathogen that could cause pneumonia and bacte...
Antibiotic misuse and overuse has prompted bacteria to rapidly develop resistance, thereby hindering...
Bacterial vaginosis (BV) is the most frequent vaginal infection in women of reproductive age. It is ...
Biofilm formation is a common strategy utilized by bacterial pathogens to establish persistence in a...
AbstractBacteria in most environments encase themselves in a hydrated matrix of polysaccharide and p...
With widespread abuse of antibiotics, bacterial resistance has increasingly become a serious threat....
Staphylococcus aureus is one of the most relevant opportunistic pathogens involved in many biofilm-a...
tissues and form biofilms. Significantly, these biofilms are a contributing mechanism of antibiotic ...
<div><p>Staphylococcal biofilms are a major concern in both clinical and food settings because they ...
<p>Shiga toxin (Stx) producing E. coli (STEC) such as Enterohemorrhagic E. coli (EHEC) are the major...
Peptidoglycan lytic enzymes (endolysins) induce bacterial host cell lysis in the late phase of the l...
The formation of a Pseudomonas aeruginosa biofilm, a complex structure enclosing bacterial cells in ...