MATHEMATICAL MODELS OF DENGUE TRANSMISSION DYNAMICS WITH VACCINATION AND WOLBACHIA PARAMETERS AND SEASONAL ASPECTS

The Aedes aegypti mosquito is the main carrier of dengue virus transmission to humans. In this study, a mathematical model for the transmission of the dengue virus is constructed using vaccination and Wolbachia parameters in an attempt to control the virus's spread. Furthermore, the fundamental reproduction number is set as a parameter of the infection threshold. Based on the stability of the equilibrium point analysis, it is found that the disease-free equilibrium point is locally asymptotically stable if . Then, a mathematical model of dengue was created by examining the seasonal aspect and adding a periodic term to the mosquito birth rate. Dengue virus transmission in mosquito populations is controlled by air temperature in addition to seasonal variables. In this study, three weather scenarios were simulated: scenario 1 for cold weather (air temperature 14 °C), scenario 2 for hot weather (air temperature 26 °C), and scenario 3 for moderate weather (air temperature between 14 and 26 °C)