Diffuse Large B Cell Lymphoma Mimicking a Large Soft Tissue Sarcoma of the Shoulder Case report in a 42 years old man, follow-up and review of literature

There are different complex anatomical structures in the shoulder and axillary regions, many of which can give rise to neoplasms. Lymphomas with the involvement of soft tissues as a primary event are very rare. The published studies have a small sample size, most of them as case reports. We want to highlight and draw attention to the clinicians, surgeons, pathologists and all the doctors to pick up this pathology in the differential diagnosis in a tumor which is first suspected to be a soft tissue sarcoma. We report a rare case of shoulder pain in a patient affected by a Diffuse Large B-Cell Lymphoma (DLBCL), of the left shoulder, his follow-up and a review literature of the shoulder lymphoma.Keywords: Diffuse large B cell lymphoma (DLBCL), immunohistochemistry, soft tissue sarcoma