International audienceFor measuring gamma rays from low energy to high energy and cover the gap between 1 MeV and 300 MeV in space measurements, Time Projection Chambers (TPC) are a promising solution. In order to read the data out of these TPCs, one needs a dedicated electronics to be flexible to cover a wide range of detectors types, with a good resolution over a large dynamic range of incoming charges. The ASTRE chip, a radiation tolerant chip for these applications is described in this article. This Application Specified Integrated Circuit (ASIC) permits the amplification, filtering, triggering and analog storage of 512 samples at a flexible sampling frequency up to 100 MHz. The power consumption is less than 10 mW/channel, with 64 chan...